SRP6007

NT-3 from mouse

recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)

• 同義詞: HDNF, NGF-2, NT-3, Nerve growth factor-2, Neurotrophic factor
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 生物源: mouse
• 重組細胞: expressed in E. coli
• 化驗: ≥97% (HPLC); ≥97% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: 13.6 kDa
• 包裝: pkg of 10 μg
• 雜質: Endotoxin, tested
• NCBI登錄號: P20181
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: mouse ... NTF3(18205)

描述

一般說明

NT-3 (neurotrophin-3) is a member of the family of trophic factors, called neurotrophins. This family also includes NGF (nerve growth factor), BDNF (brain-derived neurotrophic factor), and NT-4. NT-3 is the most abundantly expressed neurotrophin during early development.
Murine NT-3 produced from Escherichia coli contains 119 amino acid and having a molecular mass is 13.6kDa.

應用

NT-3 (neurotrophin-3) has been used for the ex vivo treatment of skin punches obtained from rat and human samples.

生化／生理作用

Study in mice show that NT-3 (neurotrophin-3), along with BDNF (brain-derived neurotrohpic factor), is essential for inner ear development. In vitro motor, enteric, primary sensory, sympathetic, locus coeruleus, cerebellar and hippocampal neurons are responsive to NT-3. Mice null for NT-3 show significant deficiency in sympathetic and sensory nerve populations. In mice, post birth up-regulation of NT-3 induces a second wave of dopaminergic amacrine cell genesis.

外觀

Sterile filtered and lyophilized powder

重構

Centrifuge the vial prior to opening. Reconstitute in H?O to a concentration of 0.1-1.0 mg/ml.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable