推薦產品
product name
NGF-β 来源于大鼠, recombinant, expressed in Sf21 cells, lyophilized powder, suitable for cell culture
生物源
rat
品質等級
重組細胞
expressed in Sf21 cells
化驗
≥97% (SDS-PAGE)
形狀
lyophilized powder
效力
0.15-3.00 ng/mL EC50
包裝
pkg of 0.1 mg
技術
cell culture | mammalian: suitable
雜質
endotoxin, tested
溶解度
water: soluble 0.1 g/L at 20 °C
UniProt登錄號
儲存溫度
−20°C
基因資訊
rat ... NGF(4803)
尋找類似的產品？ 前往 產品比較指南
相關類別
一般說明
NGFβ（神经生长因子β）是一种参与信号转导的蛋白质，表达于多种组织中，如胎盘、尿路上皮和膀胱平滑肌细胞。它是一种神经营养因子，属于NGF家族。
應用
大鼠NGF-β被用于以下应用：
- 制备DMEM培养基（用于PC12细胞的培养和分化）
- 蛋白质免疫印迹分析
- 制备分化培养基（采用DMEM制备，NGF-β是其中一种成分）
- 细胞培养和处理（用于神经元分化）
- 制备储液
生化／生理作用
NGFβ（神经生长因子β）对神经元的分化和存活至关重要。它在神经系统的发育和维持中也具有关键作用。它还参与血管生成，并促进肿瘤发生，如口腔癌、乳腺癌和前列腺癌。它是用于诊断间质性膀胱炎/膀胱疼痛综合征（IC/PBS）和膀胱过度活动症（OAB）的潜在标记物，还可能有助于决定这些疾病的治疗方法。它可能与胎盘功能的变化有关，因为NGF信号传导受到产前抑郁和选择性血清素再摄取抑制剂（SSRI）治疗的影响。
外觀
本品是从0.2 μm过滤溶液中冻干的，溶剂为PBS和1M NaCl，含有50 μg牛血清白蛋白/1 μg细胞因子
分析報告
使用因子依赖性人红白血病细胞系TF-1，在细胞增殖测定中测定生物活性。
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Zhe Gong et al.
Journal of neuroinflammation, 15(1), 242-242 (2018-08-30)
Nod-like receptor protein 3 (NLRP3) inflammasome is a crucial factor in mediating inflammatory responses after cerebral ischemia/reperfusion (I/R), but the cellular location of NLRP3 inflammasome in cerebral I/R has yet come to a conclusion, and there is still no specific
Guangyi Zhao et al.
Molecular medicine reports, 16(4), 4678-4684 (2017-08-30)
The present study aimed to investigate the effect of exogenous nerve growth factor (NGF) pretreatment on demyelination in the spinal cord of lidocaine‑treated rats, and explored the potential neuroprotective mechanisms of NGF. A total of 36 rats were randomly assigned
Xiao-Ping Huang et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 89, 124-134 (2017-02-22)
The aim of this study was to explore the effect by which the combination of Astragaloside IV (AST IV) and Ginsenoside Rg1 (Rg1) resisted autophagic injury in PC12 cells induced by oxygen glucose deprivation/reoxygenation (OGD/R). We studied the nature of
A Khodorova et al.
Neuroscience, 254, 312-323 (2013-10-08)
Nerve growth factor (NGF) augments the excitability of isolated rat sensory neurons through activation of the p75 neurotrophin receptor (p75(NTR)) and its downstream sphingomyelin signaling cascade, wherein neutral sphingomyelinase(s) (nSMase), ceramide, and the atypical protein-kinase C (aPKC), protein-kinase M zeta
Fatima AlZahra'a Alatraktchi et al.
Sensors (Basel, Switzerland), 14(11), 22128-22139 (2014-11-26)
This article presents a novel membrane-based sensor for real-time electrochemical investigations of cellular- or tissue cultures. The membrane sensor enables recording of electrical signals from a cell culture without any signal dilution, thus avoiding loss of sensitivity. Moreover, the porosity
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務