SML3494

β-Benzamide adenine dinucleotide sodium salt

≥95% (HPLC)

• 同義詞: Adenosine 5′-(trihydrogen diphosphate) P′→5′-ester with 3-β-D-ribofuranosylbenzamide sodium salt, BAD, benzamide adenine dinucleotide sodium salt
• 經驗公式（希爾表示法）: C₂₂H₂₆N₆O₁₄P₂Na₂
• 分子量：: 706.40
• 分類程式碼代碼: 51111800
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to beige
• 儲存溫度: -10 to -25°C
• SMILES 字串: O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N(C=N3)C4=C3C(N)=NC=N4)O2)(O[Na])=O)(O[Na])=O)O[C@H]1C5=CC(C(N)=O)=CC=C5

描述

生化／生理作用

β-Benzamide adenine dinucleotide (BAD), an analogue of nicotinamide adenine dinucleotide (β-NAD+), is an active metabolite of benzamide riboside and a potent inhibitor of inosine 5′-monophosphate dehydrogenase (IMPDH). Also, β-Benzamide adenine dinucleotide is a non-hydrolysable substrate/inhibitor of NADases and PARP enzymes. A higher concentration (Ki = 90 μM) it inhibits human NAD kinase.

Analogue of nicotinamide adenine dinucleotide (β-NAD+); inhibitor of inosine 5′-monophosphate dehydrogenase (IMPDH)

安全資訊

• 儲存類別代碼: 11 - Combustible Solids