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SML0337

Sigma-Aldrich

S-烯丙基-L-半胱氨酸

≥98% (HPLC)

同義詞:

L-脱氧阿洛糖, S-烯丙基-半胱氨酸, S-烯丙基半胱氨酸, SAC

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About This Item

經驗公式(希爾表示法):
C6H11NO2S
CAS號碼:
分子量::
161.22
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

光學活性

[α]/D -8 to -15°, c = 1 in H2O

顏色

white to beige

溶解度

H2O: >10 mg/mL

儲存溫度

−20°C

SMILES 字串

N[C@@H](CSCC=C)C(O)=O

InChI

1S/C6H11NO2S/c1-2-3-10-4-5(7)6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m0/s1

InChI 密鑰

ZFAHNWWNDFHPOH-YFKPBYRVSA-N

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一般說明

S-烯丙基- L -半胱氨酸具有抗炎特性。它抑制氧化强化剂酶并螯合金属。S-烯丙基- L -半胱氨酸具有降血糖和降低胆固醇的作用。 它可以防止细胞凋亡,降低诱导型一氧化氮合酶的活性,并阻断核因子κB的活性。

生化/生理作用

S-烯丙基-L-半胱氨酸是在大蒜中发现的含硫氨基酸,具有抗氧化、抗癌、抗肝毒、神经保护和神经营养活性。S-烯丙基-L-半胱氨酸在缺血性损伤和阿尔茨海默病等多种动物模型中具有有效活性。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Julio César Tobón-Velasco et al.
Free radical biology & medicine, 53(5), 1024-1040 (2012-07-12)
Pharmacological activation at the basal ganglia of the transcription factor Nrf2, guardian of redox homeostasis, holds a strong promise for the slow progression of Parkinson's disease (PD). However, a potent Nrf2 activator in the brain still must be found. In
Mei-chin Mong et al.
Journal of agricultural and food chemistry, 60(12), 3158-3165 (2012-03-08)
Renal protection of s-allyl cysteine (SAC) and s-propyl cysteine (SPC) in diabetic mice against inflammatory injury was examined. Each agent at 0.5 and 1 g/L was added to the drinking water for 10 weeks. SAC or SPC intake significantly reduced
Kevin T P Ng et al.
PloS one, 7(2), e31655-e31655 (2012-03-06)
Hepatocellular carcinoma (HCC) is highly malignant and metastatic. Currently, there is no effective chemotherapy for patients with advanced HCC leading to an urgent need to seek for novel therapeutic options. We aimed to investigate the effect of a garlic derivative
Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease: Prevention and Therapy (2014)
Patricia Rojas et al.
The Journal of nutritional biochemistry, 22(10), 937-944 (2010-12-31)
S-Allylcysteine (SAC), the most abundant organosulfur compound in aged garlic extract, has multifunctional activity via different mechanisms and neuroprotective effects that are exerted probably via its antioxidant or free radical scavenger action. The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mouse has been the most widely

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