SCP0216

Plasminogen Activator Substrate

• 經驗公式（希爾表示法）: C₂₈H₄₁N₇O₅
• 分子量：: 555.67
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 化驗: ≥95% (HPLC)
• 形狀: lyophilized
• 成份: Peptide Content, ≥80%
• 儲存條件: protect from light
• 儲存溫度: −20°C

描述

Amino Acid Sequence

BOC-Val-Gly-Arg-βNA

應用

Plasminogen Activator Substrate has been used as a fluorogenic thrombin substrate to measure the fluorescence released by cleavage of the thrombin substrate to assess the functional activity of the mannose-binding lectin–mannose-associated serine protease (MBL-MASP) complex.

Plasminogen Activator is a serine protease that coverts plasminogen into plasmin. Plasminogen activator may be detected using VGR peptide substrates such a BOC-VGR-βNA and Boc-Val-Gly-Arg-AMC (VGR).

生化／生理作用

Plasminogen activator (PA) is used to cure life-threatening coronary and cerebrovascular blockages. The important role of the PA system is to convert the inactive plasminogen to plasmin. However, it also plays a vital role in embryogenesis, cell migration, wound healing, inflammatory response, and apoptotic cell death. The PA system is also involved in tumor growth, angiogenesis, tumor cell invasion, migration, and metastasis in cancer patients.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable