推薦產品
product name
溶葡球菌酶 来源于溶葡萄球菌, free of DNA contaminants, suitable for Microbiome research, lyophilized powder, ≥500 units/mg protein
生物源
microbial (Staphylococcus staphylotyticus)
形狀
lyophilized powder
比活性
≥500 units/mg protein
分子量
27 kDa
特點
DNA free
運輸包裝
wet ice
儲存溫度
−20°C
尋找類似的產品? 前往 產品比較指南
應用
从葡萄球菌SAE0091中纯化的细胞外溶葡萄球菌素已经过严格的质量控制测试,以确保通过35个循环对16S和18S rDNA(使用通用引物对)进行PCR扩增时,不存在可检测水平的污染DNA。
溶葡萄球菌酶是从溶葡萄球菌的细菌培养物中分离出的锌金属酶。它对其他葡萄球菌(包括金黄色葡萄球菌)具有特异性裂解作用。1,2溶葡萄球菌素具有
己糖胺酶、酰胺酶和内肽酶活性。它裂解细胞壁中的聚甘氨酸交联,导致葡萄球菌物种的细胞裂解,但不导致其他细菌属的细胞裂解。[Pharmaceuticals 2010, 3(4), 1139-1161]
溶葡萄球菌素是一条包含246个氨基酸的多肽链,分子量为26,926 Da,等电点为9.5,(5),最适pH值为7.5。(6)
溶葡萄球菌酶是从溶葡萄球菌的细菌培养物中分离出的锌金属酶。它对其他葡萄球菌(包括金黄色葡萄球菌)具有特异性裂解作用。1,2溶葡萄球菌素具有
己糖胺酶、酰胺酶和内肽酶活性。它裂解细胞壁中的聚甘氨酸交联,导致葡萄球菌物种的细胞裂解,但不导致其他细菌属的细胞裂解。[Pharmaceuticals 2010, 3(4), 1139-1161]
溶葡萄球菌素是一条包含246个氨基酸的多肽链,分子量为26,926 Da,等电点为9.5,(5),最适pH值为7.5。(6)
生化/生理作用
溶葡萄球菌素是一种分子量约为25 kDa的锌内肽酶。由于溶葡萄球菌酶能裂解 葡萄球菌 类细胞壁肽聚糖层中的聚甘氨酸交联键,它已被发现可用于细胞裂解,并具有潜在的抗菌治疗作用。活性的最优pH值:~7.5。
溶葡萄球菌素是一种分子量约为25 kDa的锌内肽酶。 由于溶葡萄球菌酶能裂解 葡萄球菌 类细胞壁肽聚糖层中的聚甘氨酸交联键,它已被发现可用于细胞裂解,并具有潜在的抗菌治疗作用。
活性最佳pH:约 7.5
活性最佳pH:约 7.5
單位定義
一个单位在25℃和pH 7.5条件下,在6.0 ml反应混合物中可使金黄色葡萄球菌细胞混悬液的浊度(A620)在10分钟内由0.250降至0.125。
外觀
以冻干粉形式提供,其中含有50-70%的蛋白质,其余主要为NaCl。
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Frontiers in cellular and infection microbiology, 6, 187-187 (2017-01-14)
Background:Staphylococcus aureus (S. aureus) small colony variants (SCVs) can survive within the host intracellular milieu and are associated with chronic relapsing infections. However, it is unknown whether host invasion rates and immune responses differ between SCVs and their wild-type counterparts.
Microorganisms, 9(7) (2021-08-08)
Investigation of changes in the skin microbiome following treatment of atopic dermatitis (AD) with dupilumab may provide valuable insights into the skin microbiome as a therapeutic target. The aim of this study is to assess changes in the AD skin
PloS one, 5(12), e14209-e14209 (2010-12-15)
Ecs is an ATP-binding cassette (ABC) transporter present in aerobic and facultative anaerobic gram-positive Firmicutes. Inactivation of Bacillus subtilis Ecs causes pleiotropic changes in the bacterial phenotype including inhibition of intramembrane proteolysis. The molecule(s) transported by Ecs is (are) still
Biomaterials, 32(36), 9557-9567 (2011-10-01)
With the emergence of "super bacteria" that are resistant to antibiotics, e.g., methicillin-resistant Staphylococcus aureus, novel antimicrobial therapies are needed to prevent associated hospitalizations and deaths. Bacteriophages and bacteria use cell lytic enzymes to kill host or competing bacteria, respectively
The EMBO journal, 15(18), 4789-4797 (1996-09-16)
Microbial organisms secrete antibiotics that cause the selective destruction of specific target cells. Although the mode of action is known for many antibiotics, the mechanisms by which these molecules are directed specifically to their target cells hitherto have not been
文章
An overview of human microbiome research, workflow challenges, sequencing, library production, data analysis, and available microbiome reagents to support your research.
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務