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Merck
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重要文件

SAB4200669

Sigma-Aldrich

Anti-Digoxin antibody, Mouse monoclonal

clone DI-22, purified from hybridoma cell culture

同義詞:

异羟基洋地黄毒苷

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

mouse

品質等級

抗體表格

purified from hybridoma cell culture

抗體產品種類

primary antibodies

無性繁殖

DI-22, monoclonal

物種活性

human, mouse, rat

濃度

1.0 mg/mL
~1 mg/mL

技術

ELISA: 0.15-0.3 μg/mL

同型

IgG1

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

一般說明

Monoclonal Anti-Digoxin (mouse IgG1 isotype) is derived from the hybridoma DI-22 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with digoxin conjugated to keyhole limpet hemocyanin (KLH).

免疫原

immunized with Digoxin

應用

Monoclonal Anti-Digoxin antibody produced in mouse has been used in:
  • enzyme linked immunosorbent assay (ELISA)
  • dot blot
  • flow cytometry
  • immunofluorescence
  • DNA hybridization
  • in-situ hybridization (ISH)

生化/生理作用

Digoxin is an uncharged glycoside which is given to humans with congestive heart failure. It enhances the force of myocardial contraction. Anti-digoxin antibodies can be used to reverse the effects of digoxin.
Unlike other oral inotrope, digoxin does not promote mortality. It inhibits sodium potassium ATPase membrane pump.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Anesthesiology Keywords Review, 35-35 (2008)
High-affinity monoclonal antibodies to the cardiac glycoside, digoxin.
M M Hunter et al.
Journal of immunology (Baltimore, Md. : 1950), 129(3), 1165-1172 (1982-09-01)
Digoxin
Eichhorn EJ and Gheorghiade M
Progress in Cardiovascular Diseases, 44(4), 251-266 (2002)

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