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SAB3500901

Sigma-Aldrich

Anti-ANTHRAX PROTECTIVE ANTIGEN antibody produced in rabbit

affinity isolated antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

bacteria

濃度

1 mg/mL

技術

ELISA: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

一般說明

Anthrax toxin comprises of protective antigen (PA), lethal factor (LF) and edema factor (EF).

免疫原

Antibody was raised against a synthetic peptide corresponding to 14 amino acids at the carboxy terminus of the Anthrax protective antigen protein.

生化/生理作用

B. anthracis liberates toxins that plays a vital role in establishing and maintaining infection.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

聯結

The action of this antibody can be blocked using blocking peptide SBP3500901.

外觀

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Detection of anthrax protective antigen (PA) using europium labeled anti-PA monoclonal antibody and time-resolved fluorescence.
Stoddard RA, et al.
Journal of Immunological Methods, 408, 78-88 (2014)
Mahtab Moayeri et al.
Current opinion in microbiology, 7(1), 19-24 (2004-03-24)
Anthrax lethal toxin is a multi-functional virulence factor that has evolved to target multiple host functions to allow for optimal establishment of Bacillus anthracis infection. The toxin appears to play a role in all stages of infection, from germination to
Recognition and management of anthrax--an update.
M N Swartz
The New England journal of medicine, 345(22), 1621-1626 (2001-11-13)
K A Bradley et al.
Nature, 414(6860), 225-229 (2001-11-09)
The tripartite toxin secreted by Bacillus anthracis, the causative agent of anthrax, helps the bacterium evade the immune system and can kill the host during a systemic infection. Two components of the toxin enzymatically modify substrates within the cytosol of
Heather M Scobie et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(9), 5170-5174 (2003-04-18)
Bacillus anthracis secretes two bipartite toxins thought to be involved in anthrax pathogenesis and resulting death of the host. The current model for intoxication is that protective antigen (PA) toxin subunits bind a single group of cell-surface anthrax toxin receptors

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