跳轉至內容
Merck
全部照片(12)

Key Documents

SAB2702132

Sigma-Aldrich

抗-HIF1A 兔抗

同義詞:

HIF1-ALPHA, MOP1, PASD8, bHLHe78

登入查看組織和合約定價


About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

liquid

分子量

93 kDa

物種活性

mouse, bovine, human, rat

濃度

1 mg/mL

技術

ChIP: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: 1:100-1:1000
immunoprecipitation (IP): suitable
western blot: 500-10000

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... HIF1A(3091)

免疫原

包含与 HIF1 alpha 的 657 和 826 位氨基酸相对应的序列的重组片段

應用

建议的起始稀释度如下:ICC/IF:1:100-1:1000,IHC-Fr:稀释度由测定方法确定,IHC-P:1:100-1:1000,IP:1:100-1:570, WB:1:500-1:10000,ChIP 测定法:稀释度由测定方法确定。尚未在其他应用中进行测试。最佳工作稀释液应由终端用户通过实验确定。

生化/生理作用

缺氧诱导因子-1 (HIF1)是在低氧培养的哺乳动物细胞中发现的一种转录因子,它在对缺氧的细胞和系统体内稳态反应中起着至关重要的作用。HIF1 是由 α 亚基和 β 亚基组成的异二聚体。β 亚基已被确定为芳香烃受体核转位子(ARNT)。该基因编码 HIF-1 的 α 亚基。研究表明,该基因的天然反义转录物(aHIF)的过表达与非乳头状肾癌有关。已经鉴定出编码不同同工型的两个替代转录本。[由 RefSeq 提供]

特點和優勢

您可完全放心的评估我们的抗体。如果抗体在您的应用中没有发挥效果,我们将给予您完全的赔偿或更换抗体。 了解更多。

外觀

1XPBS,1%BSA,20% 甘油(pH 7),添加 0.025% 的 ProClin 300 作为防腐剂。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

未找到適合的產品?  

試用我們的產品選擇工具.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Aquatic Chronic 3 - Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Lehao Ren et al.
Virologica Sinica, 36(6), 1532-1542 (2021-09-15)
Viruses depend on host cellular metabolism to provide the energy and biosynthetic building blocks required for their replication. In this study, we observed that influenza A virus (H1N1), a single-stranded, negative-sense RNA virus with an eight-segmented genome, enhanced glycolysis both
Lei Yang et al.
Molecular therapy. Nucleic acids, 20, 292-307 (2020-03-22)
Recently, the identification of several circular RNAs (circRNAs) as vital regulators of microRNAs (miRNAs) underlines the increasing complexity of non-coding RNA (ncRNA)-mediated regulatory networks. This study aimed to explore the effects of mmu_circ_0000790 on the biological behaviors of pulmonary artery
Magdalena H Menhofer et al.
Cardiovascular research, 104(2), 303-314 (2014-09-23)
Inhibiting angiogenesis is a major approach in tumour therapy. To combat angiogenesis, the tubulin cytoskeleton has emerged as an interesting target in many pre- and clinical studies. Contrarily, the actin cytoskeleton has been largely neglected as a potential drug target
J S M Cuffe et al.
The Journal of physiology, 592(14), 3127-3141 (2014-05-08)
Maternal hypoxia is a common perturbation that can disrupt placental and thus fetal development, contributing to neonatal impairments. Recently, evidence has suggested that physiological outcomes are dependent upon the sex of the fetus, with males more susceptible to hypoxic insults
Junhua Mao et al.
American journal of physiology. Renal physiology, 307(9), F1023-F1032 (2014-07-06)
Podocytes play a key role in the formation of cellular crescents in experimental and human diseases. However, the underlying mechanisms for podocytes in promoting crescent formation need further investigation. Here, we demonstrated that mammalian target of rapamycin complex 1 (mTORC1)

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務