推薦產品
生物源
synthetic (organic)
品質等級
化驗
≥98%
形狀
powder
技術
HPLC: suitable
顏色
yellow
mp
62-64 °C
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[H]C(=O)\C=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C
InChI
1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
InChI 密鑰
NCYCYZXNIZJOKI-OVSJKPMPSA-N
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一般說明
全反式视黄醛是维生素A族的主要衍生物之一。各种食物都是维生素A的来源。它主要存在于肝脏和颜色鲜艳的蔬菜中。
應用
全反式视黄醛已被用于:
- 光遗传学实验
- 电生理学实验
- 研究AKR1B10(醛酮还原酶(AKR)超家族成员)对气道上皮细胞的视黄醛转化为视黄醇的影响
- 人子宫内膜基质细胞的蜕膜化
生化/生理作用
全反式视黄醛在体内可通过视黄醛脱氢酶作用转化为视黄酸。视黄酸是视黄酸受体 (RAR) 和类视色素 X 受体 (RXR) 的配体,这两种受体作为转录因子调控正常和恶性细胞的生长和分化。在可视和非可视系统中,视黄醛异构体也是发色团,可与 G-蛋白偶联跨膜蛋白家族的视蛋白结合,形成光敏受体。全反式视黄醛是一种强效的光敏剂。
包裝
密封安瓿瓶。
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All-trans retinoic acid (RA, ATRA) is a pleiotropic activation factor that regulates genes associated with normal vertebrate cellular processes such as cell differentiation, cell proliferation, apoptosis, and embryonic development.
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
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