跳轉至內容
Merck
全部照片(1)

重要文件

O0877

Sigma-Aldrich

恶喹酸

quinolone antibiotic

同義詞:

5,8-二氢-5-乙基-8-氧代-1,3-二氧戊环并[4,5-g]喹啉-7-羧酸

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C13H11NO5
CAS號碼:
分子量::
261.23
Beilstein:
620635
EC號碼:
MDL號碼:
分類程式碼代碼:
51282935
PubChem物質ID:
NACRES:
NA.85

品質等級

溶解度

0.5 M NaOH: soluble 50 mg/mL

抗生素活性譜

Gram-negative bacteria

作用方式

DNA synthesis | interferes
enzyme | inhibits

儲存溫度

2-8°C

SMILES 字串

CCN1C=C(C(O)=O)C(=O)c2cc3OCOc3cc12

InChI

1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)

InChI 密鑰

KYGZCKSPAKDVKC-UHFFFAOYSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

化学结构:喹诺酮

應用

恶喹酸被用于研究大肠杆菌(Escherichia coli)和肠沙门氏菌(Salmonella enterica)中的新型传染性抗性机制qnrA、qnrB、qnrS和aac(6′)Ib-cr。将恶喹酸加入培养基中,可用于分离阴道加德纳菌(Gardnerella vaginalis

生化/生理作用

恶喹酸是一种喹诺酮类抗生素。它是一种DNA促旋酶(拓扑异构酶II)抑制剂,可用于研究DNA缠绕和卷曲,并作为多巴胺再摄取抑制剂,用于多巴胺能神经传递过程的研究。

其他說明

5g,25g
保存于密闭容器内,置于干燥通风处。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

J Garcia de Mateos-Verchere et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 8(4), 255-259 (1999-02-03)
The antimicrobial agent oxolinic acid, injected i.p. in mice, induced a dose dependent increase in locomotor activity. This stimulation culminated at the 32 mg/kg dose and became smaller for higher doses (64-128 mg/kg). When opposed to increasing doses (50-100-200 microg/kg
J S Thompson
Journal of clinical microbiology, 21(5), 843-843 (1985-05-01)
Colistin-oxolinic acid medium is proposed as a selective isolation medium for Gardnerella vaginalis. The medium is effective in inhibiting staphylococci and gram-negative bacteria while allowing growth of G. vaginalis.
Kalliopi C Skyrianou et al.
Journal of inorganic biochemistry, 104(2), 161-170 (2009-11-27)
The mononuclear nickel(II) complexes with the first-generation quinolone antibacterial agent oxolinic acid in the presence or absence of nitrogen-donor heterocyclic ligands (2,2'-bipyridine, 1,10-phenanthroline or pyridine) have been synthesized and characterized. The experimental data suggest that oxolinic acid acts as deprotonated
Alketa Tarushi et al.
Journal of inorganic biochemistry, 103(6), 898-905 (2009-04-28)
The neutral mononuclear zinc complexes with the quinolone antibacterial drug oxolinic acid in the absence or presence of a nitrogen donor heterocyclic ligand 2,2'-bipyridine or 1,10-phenanthroline have been synthesized and characterized. The experimental data suggest that oxolinic acid is on
Takashi Aoki et al.
Marine biotechnology (New York, N.Y.), 13(4), 629-638 (2010-04-16)
Shrimp aquaculture is one of the major foodproducing industries in the world. However, it is being impacted by several problems including diseases, antibiotic use, and environmental factors. The extent of the effects of these problems in the immune system of

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務