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Merck
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重要文件

N3529

Sigma-Aldrich

NAN-190 hydrobromide

同義詞:

1-(2-Methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine hydrobromide

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About This Item

經驗公式(希爾表示法):
C23H27N3O3 · HBr
CAS號碼:
分子量::
474.39
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

SMILES 字串

Br.COc1ccccc1N2CCN(CCCCN3C(=O)c4ccccc4C3=O)CC2

InChI

1S/C23H27N3O3.BrH/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28;/h2-5,8-11H,6-7,12-17H2,1H3;1H

InChI 密鑰

AXRUEPFPTQYHQD-UHFFFAOYSA-N

基因資訊

human ... HTR1A(3350)

生化/生理作用

Potent 5-HT1A serotonin receptor antagonist active in the nM range.

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險分類

Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

Lot/Batch Number

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R L Dennis et al.
Poultry science, 91(4), 817-822 (2012-03-09)
Aggression and cannibalism in laying hens can differ in intensity and degree due to many factors, including genetics. Previous behavioral analysis of 2 strains of White Leghorns, DeKalb XL (DXL) and HGPS (a group-selected line for high group productivity and
Jaime Pei Pei Foong et al.
Neuroreport, 20(3), 325-330 (2009-02-05)
Serotonin (5-HT) plays a significant role in the regulation of intestinal secretion of water and electrolytes. The initial aim of this study was to use intracellular recording and specific antagonists to identify roles of 5-HT1A and 5-HT7 receptors of submucosal
E J Kessler et al.
Neuroscience, 154(4), 1187-1194 (2008-06-10)
Health problems can arise from de-synchrony between the external environment and the endogenous circadian rhythm, yet the circadian system is not able to quickly adjust to large, abrupt changes in the external daily cycle. In this study, we investigated the
L Rydelek-Fitzgerald et al.
Brain research, 532(1-2), 191-196 (1990-11-05)
NAN-190 has been reported to be a 5-HT1A antagonist in drug discrimination studies. In order to determine if the effect of NAN-190 was directly due to competitive inhibition at 5-HT1A receptors, 5-HT1A-mediated inhibition of adenylyl cyclase in hippocampal membranes was
James Oluwagbamigbe Fajemiroye et al.
Journal of ethnopharmacology, 141(3), 872-877 (2012-04-05)
Medicinal applications of Pimenta pseudocaryophyllus infusion as a diuretic and aphrodisiac agent as well as tranquilizer in the form of tea for the treatment of emotional tension in Brazilian folk medicine has been in practice since time immemorial. Despite its

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