全部照片(4)
About This Item
經驗公式（希爾表示法）:
C22H31NO2
CAS號碼:
分子量：:
341.49
MDL號碼:
分類程式碼代碼:
51111800
PubChem物質ID:
NACRES:
NA.77
推薦產品
生物源
synthetic (organic)
無菌
non-sterile
化驗
≥97%
形狀
powder, crystals or chunks
技術
cell culture | mammalian: suitable
溶解度
chloroform: methanol (1:1): 50 mg/mL, clear, colorless to faintly yellow (with heat)
運輸包裝
ambient
儲存溫度
2-8°C
SMILES 字串
C[C@@]12[C@](C[C@@H](C#N)[C@@H]2C(C)=O)([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC1
InChI
1S/C22H31NO2/c1-13(24)20-14(12-23)10-19-17-5-4-15-11-16(25)6-8-21(15,2)18(17)7-9-22(19,20)3/h4,14,16-20,25H,5-11H2,1-3H3/t14-,16-,17+,18-,19-,20-,21-,22-/m0/s1
InChI 密鑰
VSBHRRMYCDQLJF-ZDNYCOCVSA-N
應用
5-Pregnen-3β-ol-20-one-16α-carbonitrile has been used:
- in the induction of cytochrome P450
- as pregnane X receptor (PXR) activator in human liver cell lines.
生化／生理作用
Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
>199.9 °F - closed cup
閃點（°C）
> 93.3 °C - closed cup
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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Pregnane X receptor (PXR) is known to function as a xenobiotic sensor to regulate xenobiotic metabolism through selective transcription of genes responsible for maintaining physiological homeostasis. Here we report that the activation of PXR by pregnenolone 16α-carbonitrile (PCN) in AKR/J
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我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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