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重要文件

MAK112

Sigma-Aldrich

精氨酸酶活性检测试剂盒

sufficient for 200 colorimetric tests

同義詞:

精氨酸酶检测试剂盒

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About This Item

分類程式碼代碼:
12161503
NACRES:
NA.84

用途

sufficient for 200 colorimetric tests

檢測方法

colorimetric

相關疾病

cancer; immunological diseases; gastrointestinal diseases

儲存溫度

−20°C

基因資訊

一般說明

精氨酸酶是一种含锰酶,可催化精氨酸转化为尿素和鸟氨酸。大多数哺乳动物体内存在两种同种型精氨酸酶,其组织分布和亚细胞定位有所不同。精氨酸酶I是一种胞质蛋白,主要在肝脏中表达,在肝脏中催化尿素循环的第五步和最后一步。精氨酸酶II是一种线粒体蛋白,组织分布更广,其功能可包括一氧化氮和多胺代谢。精氨酸酶I的活性或表达降低可导致常染色体隐性遗传病高精氨酸血症。血清精氨酸酶活性增加与肝损伤和某些病理状态(如癌症)有关。精氨酸酶还参与免疫系统的多种炎症反应,例如巨噬细胞介导的细胞毒性。

應用

精氨酸酶活性检测试剂盒用于评估精氨酸酶的活性。

特點和優勢

兼容高通量的操作系统。

適合性

该试剂盒适用于检测酶制备体系、血清、血浆、组织培养物及类似样品中的精氨酸酶活性。还可用于研究药物对精氨酸酶活性的影响。

原則

在该检测中,精氨酸酶可催化精氨酸转化成尿素和鸟氨酸。产生的尿素与底物特异性反应,产生与存在的精氨酸酶活性成比例的有色产物。

象形圖

Health hazardCorrosion

訊號詞

Danger

危險分類

Aquatic Chronic 3 - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1A

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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