推薦產品
品質等級
化驗
≥99% (HPLC)
形狀
powder
溶解度
water: 5 mg/mL, clear, colorless
螢光
λex 334 nm; λem 370 nm (pH 10.4)
λex 360 nm; λem 449 nm (Reaction products)
儲存溫度
−20°C
SMILES 字串
[K+].CC1=CC(=O)Oc2cc(OS([O-])(=O)=O)ccc12
InChI
1S/C10H8O6S.K/c1-6-4-10(11)15-9-5-7(2-3-8(6)9)16-17(12,13)14;/h2-5H,1H3,(H,12,13,14);/q;+1/p-1
InChI 密鑰
CSOCSPXOODWGLJ-UHFFFAOYSA-M
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一般說明
4-甲基伞形酮硫酸酯(4MUS)作为一种通用底物,是4-甲基伞形酮(4MU)的极性代谢物。
應用
4-甲基伞形酮硫酸酯钾盐已用作偶联荧光硫代转移酶测定的底物,以从3′-磷酸腺苷5′-磷酸盐再生3′-磷酸腺苷 5′-磷酸硫酸盐(PAPS),进而测定脑苷脂硫酸转移酶(CST)的酶活性。它还用作芳香基硫酸酯酶测定/4-甲基伞形酮硫酸酯(4-MUS)测定的底物,以测试蛋白磁珠复合体的酶活性。
生化/生理作用
4-甲基伞形酮硫酸酯(4MUS)能够进行脱硫,并参与4MU的无效循环。它可以用于测定多种硫酸酯酶的活性。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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A sensitive fluorometric assay was developed for alcohol sulfotransferase (AST). This was the first continuous fluorometric assay reported for AST. It used 3'-phosphoadenosine 5'-phosphosulfate regenerated from 3-phosphoadenosine 5'-phosphate by a recombinant phenol sulfotransferase (PST) using 4-methylumbelliferyl sulfate as the sulfuryl
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The Journal of pharmacology and experimental therapeutics, 266(2), 492-499 (1993-08-01)
4-Methylumbelliferyl sulfate (4MUS), a polar metabolite of 4-methylumbelliferone (4MU), is known to undergo desulfation and participate in futile cycling with 4MU. Unusual parabolic or increasing profiles of the steady-state extraction ratio (Ess) of 4MUS with respect to concentration in rat
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