推薦產品
生物源
Salmonella enterica (serotype minnesota Re 595 Re mutant)
品質等級
形狀
lyophilized powder
雜質
<0.2% Ketodeoxyoctonate (KDO)
運輸包裝
ambient
儲存溫度
2-8°C
應用
脂质A分子组成脂质膜，锚定革兰氏阴性细菌产生的内毒素的核心组分。 脂质A分子可诱导免疫反应。 在结构上，脂质A分子由两个葡萄糖胺单元组成，两者具有不同的物种依赖性脂肪酰链数、同一性和磷酸化程度。
来自肠道沙门氏菌血清型明尼苏达Re 595的单磷酰脂质A可用于比较评估不同LPA分子和类似物中特定结构的抗原性。
来自肠道沙门氏菌血清型明尼苏达Re 595的单磷酰脂质A可用于比较评估不同LPA分子和类似物中特定结构的抗原性。
生化／生理作用
脂多糖（LPS）是革兰氏阴性细菌细胞壁的特征成分。LPS及其脂质A部分通过Toll样受体4（TLR4）刺激先天免疫系统的细胞，TLR4是Toll样受体蛋白家族的成员，该家族可识别常见的病原体相关分子模式（PAMP）。
脂质A具有免疫刺激佐剂活性，包括巨噬细胞、T细胞和B细胞活化。 研究表明，脂质A对Th2的刺激性比对Th1的大。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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