SML0608

A-412997 二盐酸盐

≥98% (HPLC)

• 同義詞: N-(3-Methylphenyl)-4-(2-pyridinyl)-1-piperidineacetamide dihydrochloride
• 經驗公式（希爾表示法）: C₁₉H₂₃N₃O · 2HCl
• CAS號碼: 1347744-96-0
• 分子量：: 382.33
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to beige
• 溶解度: H₂O: 20 mg/mL, clear
• 儲存溫度: room temp
• SMILES 字串: Cl.Cl.N2(CCC(CC2)c3ncccc3)CC(=O)Nc1cc(ccc1)C
• InChI: 1S/C19H23N3O.2ClH/c1-15-5-4-6-17(13-15)21-19(23)14-22-11-8-16(9-12-22)18-7-2-3-10-20-18;;/h2-7,10,13,16H,8-9,11-12,14H2,1H3,(H,21,23);2*1H
• InChI 密鑰: KIGNSSHMCNBHQX-UHFFFAOYSA-N

描述

生化／生理作用

A-412997 is a selective D4 agonist with Ki values of 12 and 7.9 nM for the rat and human receptors, and no affinity for other dopamine receptors at concentrations up to 1 mM. A-412997 improves short term memory and cognitive properties in rodent models.

A-412997 is a selective D4 agonist.

特點和優勢

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301,H315,H319,H335
• 防範說明: P261 - P264 - P270 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable