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Merck
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重要文件

I8782

Sigma-Aldrich

Interferon αA from mouse

≥95%, recombinant, expressed in E. coli, buffered aqueous solution, suitable for cell culture

同義詞:

IFN-αA

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

mouse

品質等級

重組細胞

expressed in E. coli

化驗

≥95%

形狀

buffered aqueous solution

分子量

20 kDa

技術

cell culture | mammalian: suitable

顏色

colorless

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

mouse ... Ifna3(110218)

生化/生理作用

Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities.
Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities. Type I Interferons are a closely related family of 165-172 amino acid proteins that are produced by leukocytes (α subtypes), fibroblasts (β subtypes), lymphocytes (ω subtypes) and ruminant embryos (τ subtypes). Interferon induces a variety of effects on target cells including antiviral, antiproliferative and immunomodulatory activities.

包裝

Minimum 1x105 units/vial.

外觀

Solution in phosphate buffered saline containing 0.1% bovine serum albumin.

分析報告

The biological activity is determined in the cytopathic effect inhibition assay using mouse L929 cells with encephalomyocarditis virus. The cytopathic effect of 50% is produced with approximately 1 unit/ml interferon. The units are determined with respect to NIH international standard reference for mouse interferon α.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Interferon standards and general abbreviations.
S Pestka
Methods in enzymology, 119, 14-23 (1986-01-01)
A convenient and rapid cytopathic effect inhibition assay for interferon.
P C Familletti et al.
Methods in enzymology, 78(Pt A), 387-394 (1981-01-01)
S Rubinstein et al.
Journal of virology, 37(2), 755-758 (1981-02-01)
A convenient assay for interferons based on reduction of cytopathic effect was developed. The number of manipulations and the lengths of the various incubation steps were reduced to a minimum. The assay is simple to perform and can be completed

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