推薦產品
生物源
human
品質等級
重組細胞
expressed in E. coli
化驗
≥95%
形狀
buffered aqueous solution
分子量
19 kDa
包裝
pkg of 20 μg
濃度
≥0.2 mg/mL
技術
cell culture | mammalian: suitable
雜質
endotoxin, tested
顏色
colorless
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... IFNA2(3440)
相關類別
應用
人干扰素-αA已被用于：
- 研究基孔肯亚病毒对干扰素介导的JAK（Janus激酶）-STAT（信号转导和转录活化因子）信号的影响
- 研究干扰素-α和PRK2（蛋白激酶C相关激酶2）抑制剂对丙型肝炎病毒复制的影响
- 比较红曲霉色素衍生物对丙型肝炎病毒复制的影响
生化／生理作用
具有抗病毒、抗增殖、免疫调节和促炎活性的细胞因子。
具有抗病毒、抗增殖、免疫调节和促炎活性的细胞因子。I型干扰素是由白细胞（α亚型），成纤维细胞（β亚型），淋巴细胞（ω亚型）和反刍动物胚胎（τ亚型）产生的165-172个氨基酸蛋白的密切相关家族。干扰素可诱导靶细胞产生多种作用，包括抗病毒、抗增殖和免疫调节活性。
外觀
以5 mM 乙酸钠，pH 4.0中的溶液形式提供。
分析報告
在细胞病变效应抑制试验中，使用含有水疱性口炎病毒（VSV）的MDBK细胞测定生物活性。用1单位/ml干扰素可产生50%的细胞病变效应。单位是根据WHO人干扰素αA国际标准参考确定的。
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves
客戶也查看了
S-J Kim et al.
Journal of viral hepatitis, 16(10), 697-704 (2009-02-27)
Hepatitis C virus (HCV) infection is a serious threat to human health worldwide. In spite of the continued search for specific and effective anti-HCV therapies, the rapid emergence of drug-resistance variants has been hampering the development of anti-HCV drugs designed
Ji-Min Sun et al.
The Journal of antimicrobial chemotherapy, 67(1), 49-58 (2011-11-15)
Hepatitis C virus (HCV) infection causes chronic liver disease and is a major public health problem worldwide. The aim of this study was to evaluate the potential of Monascus pigment derivatives, which were derived from a microbial secondary metabolite synthesized
Jelke J Fros et al.
Journal of virology, 84(20), 10877-10887 (2010-08-06)
Chikungunya virus (CHIKV) is an emerging human pathogen transmitted by mosquitoes. Like that of other alphaviruses, CHIKV replication causes general host shutoff, leading to severe cytopathicity in mammalian cells, and inhibits the ability of infected cells to respond to interferon
A convenient and rapid cytopathic effect inhibition assay for interferon.
P C Familletti et al.
Methods in enzymology, 78(Pt A), 387-394 (1981-01-01)
S Rubinstein et al.
Journal of virology, 37(2), 755-758 (1981-02-01)
A convenient assay for interferons based on reduction of cytopathic effect was developed. The number of manipulations and the lengths of the various incubation steps were reduced to a minimum. The assay is simple to perform and can be completed
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務