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Key Documents

I3636

Sigma-Aldrich

吖啶诱变剂ICR 191

同義詞:

6-氯-9- [3-(2-氯乙胺)丙胺基]-2-甲氧基吖啶 二盐酸盐

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About This Item

經驗公式(希爾表示法):
C19H21Cl2N3O · 2HCl
CAS號碼:
分子量::
451.22
Beilstein:
8176205
EC號碼:
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.32

溶解度

DMSO: soluble

品質等級

適合性

suitable for Ames test in Salmonella and E. coli (Frameshift mutagenic standard)

儲存溫度

2-8°C

SMILES 字串

Cl[H].Cl[H].COc1ccc2nc3cc(Cl)ccc3c(NCCCNCCCl)c2c1

InChI

1S/C19H21Cl2N3O.2ClH/c1-25-14-4-6-17-16(12-14)19(23-9-2-8-22-10-7-20)15-5-3-13(21)11-18(15)24-17;;/h3-6,11-12,22H,2,7-10H2,1H3,(H,23,24);2*1H

InChI 密鑰

LMEMIKWTNPWYMI-UHFFFAOYSA-N

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相關類別

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B

儲存類別代碼

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


分析證明 (COA)

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Environmental and molecular mutagenesis, 23(2), 96-100 (1994-01-01)
Human TK6 lymphoblasts were treated with the acridine derivative ICR-191, and mutants at the hprt locus were isolated. Mutant hprt cDNA was reverse-transcribed from mRNA, amplified by polymerase chain reaction (PCR), and sequenced. Additions of single G:C base pairs (+1

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