SMB01383

PhIP

≥95% (HPLC)

• 同義詞: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
• 經驗公式（希爾表示法）: C₁₃H₁₂N₄
• CAS號碼: 105650-23-5
• 分子量：: 224.26
• MDL號碼: MFCD00210745
• 分類程式碼代碼: 12352100
• NACRES: NA.28

屬性

• 生物源: synthetic
• 品質等級: 200
• 化驗: ≥95% (HPLC)
• 形狀: solid
• 運輸包裝: 2-8°C
• 儲存溫度: 2-8°C
• SMILES 字串: NC1=NC2=NC=C(C3=CC=CC=C3)C=C2N1C
• InChI: 1S/C13H12N4/c1-17-11-7-10(9-5-3-2-4-6-9)8-15-12(11)16-13(17)14/h2-8H,1H3,(H2,14,15,16)
• InChI 密鑰: UQVKZNNCIHJZLS-UHFFFAOYSA-N

描述

一般說明

PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) is a dietary genotoxic carcinogen formed in heat processed meat and fish via the Maillard reaction. PhIP is a primary metabolite activated by CYP1A2 and N-acetyltransferase 1 or sulfotransferase to DNA reactive metabolite.

生化／生理作用

Carcinogen developed in grilled meats. Induces breast and colon cancer in rats.

安全資訊

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H301,H315,H319,H335,H351
• 防範說明: P202 - P261 - P264 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable