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Merck
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重要文件

GW22768

Sigma-Aldrich

Anti-MAPK1/ERK2 Antibody

chicken polyclonal

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

產品名稱

Anti-MAPK1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution

生物源

chicken

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

rat, mouse, human

製造商/商標名

Genway 15-288-22768

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... MAPK1(5594)

免疫原

Immunogen Sequence: GI # 20986531, sequence 232-360
Recombinant mitogen-activated protein kinase 1

應用

Anti-MAPK1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Mitogen-activated protein kinase 1 is an enzyme encoded by the MAPK1 gene in humans. RAS/mitogen - activated protein kinase (MAPK) pathway plays a crucial role in embryonic and postnatal development. It is also associated with COPD (chronic obstructive pulmonary disease) and p38 MAPK may have a a potential target for the treatment of COPD.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Natalia Bezniakow et al.
Developmental period medicine, 18(3), 285-296 (2014-09-04)
The RASopathies are a class of developmental syndromes. Each of them exhibits distinctive phenotypic features, although there are numerous overlapping clinical manifestations that include: dysmorphic craniofacial features, congenital cardiac defects, skin abnormalities, varying degrees of intellectual disability and increased risk
Cuiping Huang et al.
Medical science monitor : international medical journal of experimental and clinical research, 19, 1229-1235 (2014-01-03)
Inflammation and remodeling of the small airways are major determinants of the progression and severity of COPD. The present study explored the correlation between sputum p38 mitogen-activated protein kinase (MAPK) activity and airway inflammation and reduction of lung function in
Gwendolyn I Humphreys et al.
PloS one, 9(11), e111975-e111975 (2014-11-06)
17β-estradiol (E2) plays critical roles in a number of target tissues including the mammary gland, reproductive tract, bone, and brain. Although it is clear that E2 reduces inflammation and ischemia-induced damage in the cerebral cortex, the molecular mechanisms mediating the
Cynthia L Neben et al.
Human molecular genetics, 23(21), 5659-5671 (2014-06-09)
Fibroblast growth factor receptor 2 (FGFR2) promotes osteoprogenitor proliferation and differentiation during bone development, yet how the receptor elicits these distinct cellular responses remains unclear. Analysis of the FGFR2-skeletal disorder bent bone dysplasia syndrome (BBDS) demonstrates that FGFR2, in addition
Ji-Hee Kim et al.
Oncology reports, 31(6), 2708-2712 (2014-05-03)
Protein tyrosine kinase 7 (PTK7) is a catalytically inactive receptor tyrosine kinase that is also known as colon carcinoma kinase-4 (CCK-4). Recent reports have shown that PTK7 plays an important role in carcinogenesis, and it is known to be upregulated

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