推薦產品
化驗
≥98% (HPLC)
形狀
solid
溶解度
DMSO: >10 mg/mL
儲存溫度
room temp
SMILES 字串
Fc1cc(F)c2NC([C@@H]3CC=C[C@@H]3c2c1)c4cccnc4
InChI
1S/C17H14F2N2/c18-11-7-14-12-4-1-5-13(12)16(10-3-2-6-20-9-10)21-17(14)15(19)8-11/h1-4,6-9,12-13,16,21H,5H2/t12-,13+,16?/m0/s1
InChI 密鑰
NJZHEQOUHLZCOX-FTLRAWMYSA-N
應用
杀真菌剂 A 可用作逆转录分析的抑制剂，并被用作 HeLa 细胞中高尔基体特异性布雷菲德菌素 A 抗鸟嘌呤核苷酸交换因子 1 蛋白（GBF1）的抑制剂。
生化／生理作用
Golgicide A 是一种有效的、高特异性的、可逆的顺式高尔基 体 ArfGEF GBF1 抑制剂。Arf 蛋白是介导小泡运输的小鸟苷三磷酸酶（GTPase）Ras 超家族的成员。Golgicide A 在 Arf1 和 GBF1 Sec7 结构域之间形成的界面裂缝内结合。Golgicide A 是一种独特而强大的工具，可用于进一步阐明高尔基体内组装和运输的机制，而 Dynasore 可用于研究动力蛋白介导的网格蛋白涂层形成动力学。
特點和優勢
这种化合物是环核苷酸研究的特色产品。点击此处发现更多特色环核苷酸产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Silke Peter et al.
BMC genomics, 18(1), 859-859 (2017-11-12)
Pseudomonas putida is a Gram-negative, non-fermenting bacterium frequently encountered in various environmental niches. P. putida rarely causes disease in humans, though serious infections and outbreaks have been reported from time to time. Some have suggested that P. putida functions as
Ying Wu et al.
BMC genomics, 19(1), 705-705 (2018-09-27)
Powdery mildew (PM) is one of the most important and widespread plant diseases caused by biotrophic fungi. Notably, while monocot (grass) PM fungi exhibit high-level of host-specialization, many dicot PM fungi display a broad host range. To understand such distinct
Shi-Min Yuan et al.
Brazilian journal of cardiovascular surgery, 34(4), 472-479 (2019-08-28)
The roles that aortitis plays in the development of annuloaortic ectasia (AAE) remain uncertain, while clinical features of AAE in arteritis are largely unknown. This study was designed to highlight the clinical features of AAE, the treatments of choice, and
Hilary C Martin et al.
Molecular biology and evolution, 35(5), 1238-1252 (2018-04-25)
The platypus is an egg-laying mammal which, alongside the echidna, occupies a unique place in the mammalian phylogenetic tree. Despite widespread interest in its unusual biology, little is known about its population structure or recent evolutionary history. To provide new
Sravani Banerjee et al.
PLoS pathogens, 14(5), e1007086-e1007086 (2018-05-22)
RNA viruses induce specialized membranous structures for use in genome replication. These structures are often referred to as replication organelles (ROs). ROs exhibit distinct lipid composition relative to other cellular membranes. In many picornaviruses, phosphatidylinositol-4-phosphate (PI4P) is a marker of
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務