推薦產品
product name
DL-α-二氟甲基鸟氨酸 盐酸盐 水合物, solid, ≥97% (NMR)
化驗
≥97% (NMR)
形狀
solid
顏色
white
溶解度
DMSO: >10 mg/mL
H2O: >10 mg/mL
SMILES 字串
O.Cl.NCCCC(N)(C(F)F)C(O)=O
InChI
1S/C6H12F2N2O2.ClH.H2O/c7-4(8)6(10,5(11)12)2-1-3-9;;/h4H,1-3,9-10H2,(H,11,12);1H;1H2
InChI 密鑰
FJPAMFNRCFEGSD-UHFFFAOYSA-N
基因資訊
human ... ODC1(4953)
一般說明
二氟甲基鸟氨酸是一种氟化鸟氨酸类似物,可作为多胺生物合成的限速酶。它可用于治疗女性面部多毛症和人类非洲锥虫病。二氟甲基鸟氨酸可作为神经母细胞瘤和结直肠癌的化学预防和治疗药物。对哺乳动物细胞和组织具有细胞生长抑制作用。
應用
DL-α-二氟甲基鸟氨酸盐酸水合物已用于降低精氨酸对细胞的增殖效果。它还用于研究双酚A(BPA)对已建立的绵羊滋养外胚层(oTr1)细胞系迁移的影响。
生化/生理作用
二氟甲基鸟氨酸(依氟鸟氨酸)通过选择性、不可逆抑制鸟氨酸脱羧酶 (ODC) 抑制多胺生物合成。一种阻止血管生成的化学保护剂。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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