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About This Item
經驗公式（希爾表示法）:
C28H32F2N2O · 2HCl
CAS號碼:
分子量：:
523.49
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
solid
顏色
white
溶解度
DMSO: >5 mg/mL (Solutions freshly prepared daily)
SMILES 字串
Cl.Cl.Fc1ccc(cc1)C(OCCN2CCN(CCCc3ccccc3)CC2)c4ccc(F)cc4
InChI
1S/C28H32F2N2O.2ClH/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23;;/h1-3,5-6,8-15,28H,4,7,16-22H2;2*1H
InChI 密鑰
MIBSKSYCRFWIRU-UHFFFAOYSA-N
基因資訊
human ... DRD1(1812) , DRD2(1813) , DRD3(1814) , DRD4(1815) , DRD5(1816)
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應用
GBR 12909二盐酸盐可作为多巴胺转运体(DAT)抑制剂，用于：
- 研究其对小鼠纹状体中脂多糖(LPS)诱导的促炎性细胞因子mRNA表达的影响
- 研究其对斑马鱼大脑神经递质释放的影响
- 小鼠纹状体的多巴胺摄取试验
生化／生理作用
GBR 12909可作为药物治疗可卡因上瘾。
GBR 12909是一种具有类似可卡因行为效应的高度选择性多巴胺再摄取抑制剂。
特點和優勢
该化合物收录于 受体分类和信号转导手册的《生物胺转运体 》页面。想要浏览手册的其他页面， 请单击此处。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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