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P8013

Sigma-Aldrich

Pargyline 盐酸盐

同義詞:

N-甲基-N-2-丙炔基苄胺 盐酸盐, N-甲基-N-丙炔基苄胺 盐酸盐

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About This Item

線性公式:
C6H5CH2N(CH3)CH2C≡CH·HCl
CAS號碼:
分子量::
195.69
Beilstein:
3699487
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

生物源

synthetic

化驗

98% (TLC)

形狀

powder or crystals

mp

160-163 °C (lit.)

溶解度

water: 50 mg/mL, clear, colorless to faintly yellow

儲存溫度

−20°C

SMILES 字串

Cl[H].CN(CC#C)Cc1ccccc1

InChI

1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H

InChI 密鑰

BCXCABRDBBWWGY-UHFFFAOYSA-N

基因資訊

尋找類似的產品? 前往 產品比較指南

應用

优降宁盐酸盐已用于:
  • 用作组蛋白脱甲基酶抑制剂来治疗单核细胞,以研究各种抑制剂是否会影响训练
  • 以最大程度地吸收实验大鼠的多巴胺能神经元(DA)神经元
  • 以研究其对核盘菌核髓质组织变色的影响

生化/生理作用

优降宁盐酸盐可用作组蛋白脱甲基酶抑制剂。它具有抗高血压作用。
选择性 MAO-B 抑制剂。

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

防範說明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


分析證明 (COA)

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存取文件庫

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Ifrim DC, et al.
Clinical and Vaccine Immunology : CVI, 21(4), 534-545 (2014)
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Epigenomes, 4(4) (2021-04-09)
Differential DNA methylation is characteristic of gene regulatory regions, such as enhancers, which mostly constitute low or intermediate CpG content in their DNA sequence. Consequently, quantification of changes in DNA methylation at these sites is challenging. Given that DNA methylation
An update on antidepressant toxicity: an evolution of unique toxicities to master
Liebelt EL
Clinical Pediatric Emergency Medicine, 9(1), 24-34 (2008)
Resonant antidromic cortical circuit activation as a consequence of high-frequency subthalamic deep-brain stimulation
Li S, et al.
Journal of Neurophysiology, 98(6), 3525-3537 (2007)
Biochemical Pathway for the Formation of Abnormal Sclerotia of Sclerotinia sclerotiorum
Huang HC and Yeung JM
Plant Pathology, 11(1), 2-2 (2002)

文章

Epigenetic modifications are thought to occur through two key interconnected processes—DNA methylation and the covalent modification of histones.

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