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Key Documents

D0443

Sigma-Aldrich

葡聚糖酶 来源于Chaetomium erraticum

同義詞:

葡聚糖酶Plus L, 1,6-α-D-葡聚糖 6-葡聚糖水解酶

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About This Item

CAS號碼:
酶委員會編號:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

一般說明

Novozymes Corp.的产品
葡聚糖酶由许多微生物产生,包括细菌、丝状真菌和酵母。

應用

来自毛壳菌的葡聚糖酶已被用于:
  • 微载体溶解以产生药物发现用多细胞 3D 球体
  • 细菌分离物中细胞外多糖(EPS)的体外消化
  • 葡聚糖酶固定化的研究
  • 研究交替糖酶促修饰工艺条件的优化

生化/生理作用

葡聚糖酶是一种水解葡聚糖中α-(1,6)-糖苷键的内葡聚糖酶。它具有许多工业和临床应用,例如食品加工、糖修饰和药物制备。葡聚糖酶广泛用于生产交替甜菜和异麦芽寡糖(IMO),这是一种益生功能食品。从葡聚糖酶获得的低分子量葡聚糖可用作合成血容量扩充剂。葡聚糖酶可与抗体偶联以检测肿瘤细胞。它通过使牙齿中的微生物葡聚糖沉积物解聚来防止牙菌斑的发生。因此,它被用于牙科护理产品。

準備報告

通过Chaetomium erraticum的深层发酵产生的一种真菌葡聚糖酶。

分析報告

在pH 3-7范围内以及最高约70 °C的温度下稳定。对于绝大多数应用,比较适合的条件是pH 5-6且 50-60 °C的温度。

象形圖

Health hazard

訊號詞

Danger

危險聲明

防範說明

危險分類

Resp. Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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存取文件庫

Frank Alwin Erhardt et al.
Journal of biotechnology, 131(4), 440-447 (2007-09-19)
In order to facilitate the Co-Immobilization of dextransucrase and dextranase, various techniques for the immobilization of industrial endo-dextranase from Chaetomium erraticum (Novozymes A/S) were researched. Adsorption isotherms at various pH-values have been determined for bentonite (Montmorillonite), hydroxyapatite and Streamline DEAE.
F Abeille et al.
Lab on a chip, 14(18), 3510-3518 (2014-07-12)
Microfluidic bioreactors are expected to impact cell therapy and biopharmaceutical production due to their ability to control cellular microenvironments. This work presents a novel approach for continuous cell culture in a microfluidic system. Microcarriers (i.e., microbeads) are used as growth
Co-immobilization of dextransucrase and dextranase in epoxy-agarose-tailoring oligosaccharides synthesis
da Silva R, et al.
Process Biochemistry (Oxford, United Kingdom), 78, 71-81 (2019)
Young-Min Kim et al.
Applied microbiology and biotechnology, 91(2), 329-339 (2011-04-12)
Multiple forms of native and recombinant endo-dextranases (Dexs) of the glycoside hydrolase family (GH) 66 exist. The GH 66 Dex gene from Streptococcus mutans ATCC 25175 (SmDex) was expressed in Escherichia coli. The recombinant full-size (95.4 kDa) SmDex protein was digested
Mohanad Bashari et al.
Ultrasonics sonochemistry, 20(1), 155-161 (2012-07-24)
In our current research work, the effect of ultrasound irradiation on the enzymatic activity and enzymatic hydrolysis kinetic parameters of dextran catalysis by dextranase were investigated. Furthermore, the effects of ultrasound irradiation on the structure of dextranase were investigated with

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