跳轉至內容
Merck
全部照片(1)

Key Documents

C3617

Sigma-Aldrich

Anti-Casein Kinase 2β antibody, Mouse monoclonal

clone 6D5, purified from hybridoma cell culture

同義詞:

Anti-CK2β

登入查看組織和合約定價


About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.44

生物源

mouse

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

6D5, monoclonal

形狀

buffered aqueous solution

分子量

antigen ~30 kDa

物種活性

mouse, hamster, bovine, rat, human

濃度

~2 mg/mL

技術

dot blot: suitable
indirect ELISA: suitable
microarray: suitable
western blot: 2-4 μg/mL using total cell extract of HepG2 cells

同型

IgG1

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CSNK2B(1460)
mouse ... Csnk2b(13001)
rat ... Csnk2b(81650)

一般說明

Casein Kinase 2 (CK2) is a ubiquitously expressed serine/threonine kinase that has been implicated in various cellular functions such as cell death, cell cycle regulation, and mRNA synthesis. This protein kinase comprises of two catalytic α subunits and two dimeric β subunits that associate to form a heterotetrameric enzyme complex.CK2 is also involved in regulating viral infections
Monoclonal Anti-Casein Kinase 2β antibody is specific for human, bovine, rat, mouse and hamster Casein Kinase 2β (approx. 30 kDa). The antibody epitope lies within amino-acids 123-127 of human CK2β.

免疫原

recombinant human casein kinase 2β (CK2β). The antibody epitope resides within amino acids 123-127.

應用

Monoclonal Anti-Casein Kinase 2β antibody is suitable for use in indirect immunofluorescence (using A549 cells ). The product can also be used for western blot (2-4 μg/mL using total cell extract of HepG2 cells), microarray, dot blot and indirect ELISA.

生化/生理作用

Casein Kinase 2β encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha pr

外觀

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到適合的產品?  

試用我們的產品選擇工具.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

N A St-Denis et al.
Cellular and molecular life sciences : CMLS, 66(11-12), 1817-1829 (2009-04-24)
Protein kinase CK2 is a serine/threonine kinase with a multitude of protein substrates. The enzyme is ubiquitously expressed in mammalian cells, where it functions in a variety of cellular processes, including cell cycle progression, apoptosis, transcription, and viral infection. While
Wilhelm Ching et al.
Journal of virology, 86(5), 2400-2415 (2011-12-23)
The human adenovirus type 5 (HAdV5) early region 1B 55-kDa protein (E1B-55K) is a multifunctional phosphoprotein playing several critical roles during adenoviral productive infection, e.g., degradation of host cell proteins, viral late mRNA export, and inhibition of p53-mediated transcription. Many
Marc P Lussier et al.
The European journal of neuroscience, 39(7), 1148-1158 (2014-04-10)
Controlling the density of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) at synapses is essential for regulating the strength of excitatory neurotransmission. In particular, the phosphorylation of AMPARs is important for defining both synaptic expression and intracellular routing of receptors. Phosphorylation is a
Inessa Ermakova et al.
Journal of molecular biology, 330(5), 925-934 (2003-07-16)
Protein kinase CK2 (formerly called: casein kinase 2) is a heterotetrameric enzyme composed of two separate catalytic chains (CK2alpha) and a stable dimer of two non-catalytic subunits (CK2beta). CK2alpha is a highly conserved member of the superfamily of eukaryotic protein

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務