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應用
Glycophorin is the major sialylated protein of the erythrocyte membrane. Product A9791 is asialoglycophorin from human blood type MN. Glycophorin has been inserted into target cells, by electropulsation, to study resistance to natural killer cells .
生化/生理作用
M and N active glycopeptides have identical amino acid sequences, except at residues 1 and 5, and glycosylated residues 2 to 4, which contain approximately 5 sialic acid groups. The removal of sialic acid from glycophorin destroys M and N activity. Glycophorin A may be involved in the resistance of target cells to natural killing.
其他說明
Predominantly asialoglycophorin A
免責聲明
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
K el Ouagari et al.
The Journal of biological chemistry, 270(45), 26970-26975 (1995-11-10)
Glycophorin A is a protein with an abundant glycosylation (60% carbohydrate by weight), and studies have suggested that resistance of target cells to natural killing may be correlated with the level of glycophorin A expression. To assess the role of
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