推薦產品
應用
β-N-乙酰氨基葡萄糖苷酶是用于水解 N-乙酰基-β-D-氨基葡萄糖苷和 N-乙酰基-β-D-半乳糖胺的溶酶体酶。基于 β-GlcNAc 和 β-GalNAcc 的有效转糖基作用,它用于寡糖的化学酶促合成。其可能是研究阿尔茨海默病的有用工具 。来自洋刀豆的乙酰氨基葡萄糖苷酶已被用于研究生物膜的酶解离 。
生化/生理作用
这种酶,有时称为 β-N-乙酰氨基己糖苷酶,据报道可释放末端 β-连接来自多种底物的 N-乙酰葡糖胺和 N-乙酰半乳糖胺。β-N-酰基葡糖胺酶的活性可以用显色底物对硝基苯基-N-乙酰基-β-D-氨基葡萄糖苷测定。 β-N-酰基葡糖胺酶水解末端非还原性 N-乙酰基-D-己糖胺残基。这种酶含有两种主要的同工酶,Hex A(异源二聚体)和 Hex B(同源二聚体)。N-乙酰氨基葡萄糖、乙酰胺、N-2-乙酰胺基-2-脱氧葡萄糖胺、N-乙酰诺吉瑞霉素和 N-乙酰脱氧诺吉瑞霉素是已知的抑制剂。
这种酶,有时称为 β-N-乙酰氨基己糖苷酶,据报道可释放末端 β-连接来自多种底物的 N-乙酰葡糖胺和 N-乙酰半乳糖胺。
單位定義
一个单位将在 pH5.0、25 °C下每分钟将 1.0μmole 对硝基苯基 N-乙酰基-β-D-氨基葡萄糖水解成对硝基苯酚和N-乙酰基-D-葡糖胺。
外觀
2.5 M 混悬液 (NH4)2SO4,pH 7.0
分析報告
在 pH 4.0 时,对硝基苯基 β-N-乙酰氨基半乳糖在 pH 5.0 时水解速率约为对硝基苯基 β-N-乙酰氨基葡萄糖水解速率的 50%。
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Journal of medical microbiology, 55(Pt 8), 999-1008 (2006-07-20)
Matrix material was extracted from biofilms of Candida albicans and Candida tropicalis and analysed chemically. Both preparations contained carbohydrate, protein, hexosamine, phosphorus and uronic acid. However, the major component in C. albicans matrix was glucose (32%), whereas in C. tropicalis
Neurobiology of aging, 34(1), 275-285 (2012-04-17)
Deposition of β-amyloid (Aβ) as senile plaques and disrupted glucose metabolism are two main characteristics of Alzheimer's disease (AD). It is unknown, however, how these two processes are related in AD. Here we examined the relationship between O-GlcNAcylation, which is
Molecular genetics and metabolism, 108(1), 70-75 (2012-12-26)
GM2 gangliosidosis is a fatal lysosomal storage disease caused by a deficiency of β-hexosaminidase (EC 3.2.1.52). There are two major isoforms of the enzyme: hexosaminidase A composed of an α and a β subunit (encoded by HEXA and HEXB genes
Recenti progressi in medicina, 103(12), 559-563 (2012-12-22)
Cardiorenal syndrome is a pathophysiological heart and kidney disorder, in which acute or chronic dysfunction of one organ induces a damage in the other. It's a syndrome more and more often encountered in clinical practice and this implies the need
Molecular genetics and metabolism, 108(1), 65-69 (2012-11-20)
A 12 year-old female presented with a seven-year history of progressive muscle weakness, atrophy, tremor and fasciculations. Cognition was normal. Rectal biopsy revealed intracellular storage material and biochemical testing indicated low hexosaminidase activity consistent with juvenile-onset G(M2)-gangliosidosis. Genetic evaluation revealed
文章
Instructions for working with enzymes supplied as ammonium sulfate suspensions
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務