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Merck
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文件

A1757

Sigma-Aldrich

6-氮杂嘧啶

≥98%

同義詞:

6-AU, 1,2,4-三嗪-3,5(2H,4H)-二酮, 3,5-二羟基-1,2,4-三嗪, 6-氮杂-2,4-二羟基嘧啶

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About This Item

經驗公式(希爾表示法):
C3H3N3O2
CAS號碼:
分子量::
113.07
Beilstein:
116472
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51

化驗

≥98%

形狀

powder

mp

274-275 °C (lit.)

溶解度

1 M NH4OH: 50 mg/mL, clear to slightly hazy, colorless to light yellow-green

SMILES 字串

O=C1NN=CC(=O)N1

InChI

1S/C3H3N3O2/c7-2-1-4-6-3(8)5-2/h1H,(H2,5,6,7,8)

InChI 密鑰

SSPYSWLZOPCOLO-UHFFFAOYSA-N

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應用

6-氮杂尿嘧啶已用作转录抑制剂,用于研究其对终止和多聚腺苷酸化蛋白(Tpa1)和Mag1缺失细胞的活力影响。它还已用作基础培养基中的乳清酸核苷-5′-单磷酸脱羧酶(OMP脱羧酶)抑制剂,用于测定OMP脱羧酶活性。

生化/生理作用

6-氮杂尿嘧啶(6-AU)是尿嘧啶的嘧啶类似物,具有抗肿瘤活性。它可用于去除细胞内的鸟苷三磷酸(GTP)和尿苷三磷酸(UTP)两种核苷酸混合物,从而抑制各种微生物生长。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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