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Sigma-Aldrich

5(6)-Carboxynaphthofluorescein

BioReagent, suitable for fluorescence, ≥90% (HPLC)

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About This Item

經驗公式（希爾表示法）:
C29H16O7
CAS號碼:
128724-35-6
分子量：:
476.43
分類程式碼代碼:
12352200
PubChem物質ID:
329752223
NACRES:
NA.32

產品線

BioReagent

品質等級

100

化驗

≥90% (HPLC)

形狀

solid

pKa 

7.6

螢光

λex 512 nm; λem 567 nm (acid/neutral)
λex 598 nm; λem 668 nm (basic)

適合性

suitable for fluorescence

SMILES 字串

OC(=O)c1ccc2c(c1)C(=O)OC23c4ccc5cc(O)ccc5c4Oc6c3ccc7cc(O)ccc67.OC(=O)c8ccc9C(=O)OC%10(c%11ccc%12cc(O)ccc%12c%11Oc%13c%10ccc%14cc(O)ccc%13%14)c9c8

InChI

1S/2C29H16O7/c30-17-4-6-19-14(11-17)1-9-23-25(19)35-26-20-7-5-18(31)12-15(20)2-10-24(26)29(23)22-8-3-16(27(32)33)13-21(22)28(34)36-29;30-17-4-7-19-14(11-17)2-9-22-25(19)35-26-20-8-5-18(31)12-15(20)3-10-23(26)29(22)24-13-16(27(32)33)1-6-21(24)28(34)36-29/h2*1-13,30-31H,(H,32,33)

InChI 密鑰

ANUHNEJUELPITC-UHFFFAOYSA-N

應用

5(6)-Carboxynaphthofluorescein (CNF) may be used as an intravesicular pH-sensitive probe for the detection of activity, selectivity and cooperativity of ion channels such as gramicidin A.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析證明 (COA)

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D A Jankowska et al.
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Sara M Butterfield et al.
Organic & biomolecular chemistry, 7(9), 1784-1792 (2009-07-11)
The activity of synthetic pores, ion channels, transporters and carriers is usually determined with fluorescent probes in vesicles or by conductance measurements in planar lipid bilayers. Elaborating on more colorful alternatives, we here introduce 5(6)-carboxynaphthofluorescein (CNF) as an intravesicular pH
A Song et al.
Analytical chemistry, 69(5), 863-867 (1997-03-01)
A fast and durable ratiometric pH microoptode that is highly accurate, precise, sensitive, reversible, and reproducible over the physiological ranges of pH, ionic strength, and temperature has been developed. The sensing site consists of 5 (and 6)-carboxynaphthofluorescein (CNF) entrapped in

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