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17937

25-羟基维生素D₂

Name: 25-羟基维生素D<SUB>2</SUB>
Brand: SIGMA

≥95.0% (HPLC)

同義詞:

25-羟基维生素, 25-羟基麦角甾醇, 骨化二醇

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About This Item

經驗公式（希爾表示法）:

C₂₈H₄₄O₂

CAS號碼:

21343-40-8

分子量：:

412.65

Beilstein:

4716773

MDL號碼:

MFCD02683431

分類程式碼代碼:

12352205

eCl@ss:

34058017

PubChem物質ID:

57647689

NACRES:

NA.28

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生物源

synthetic

品質等級

200

化驗

≥95.0% (HPLC)

形狀

crystalline powder

顏色

white to off-white

mp

88.0-95.0 °C

儲存溫度

−70°C

SMILES 字串

[H][C@@]12CC[C@H]([C@H](C)\C=C\[C@H](C)C(C)(C)O)[C@@]1(C)CCC/C2=C\C=C3\C[C@@H](O)CCC3=C

InChI

1S/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12+,23-13-/t20-,21+,24+,25-,26+,28-/m1/s1

InChI 密鑰

KJKIIUAXZGLUND-ICCVIKJNSA-N

生化／生理作用

麦角钙化醇（维生素D2）在体内通过羟基化反应而活化，生成25-羟基麦角钙化醇和1α,25-二羟基钙化醇。活化的维生素D2分子可用于广泛的研究，以评估其对免疫功能和钙稳态等功能的影响。

包裝

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象形圖

GHS06,GHS08

訊號詞

Danger

危險聲明

H301 + H311,H330,H372

防範說明

P260 - P264 - P280 - P302 + P352 + P312 - P304 + P340 + P310 - P314

危險分類

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

分析證明 (COA)

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A 12-week double-blind randomized clinical trial of vitamin D₃ supplementation on body fat mass in healthy overweight and obese women.

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Nutrition journal, 11, 78-78 (2012-09-25)

Vitamin D concentrations are linked to body composition indices, particularly body fat mass. Relationships between hypovitaminosis D and obesity, described by both BMI and waist circumference, have been mentioned. We have investigated the effect of a 12-week vitamin D3 supplementation

Toll-like receptor 8 ligands activate a vitamin D mediated autophagic response that inhibits human immunodeficiency virus type 1.

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PLoS pathogens, 8(11), e1003017-e1003017 (2012-11-21)

Toll-like receptors (TLR) are important in recognizing microbial pathogens and triggering host innate immune responses, including autophagy, and in the mediation of immune activation during human immunodeficiency virus type-1 (HIV) infection. We report here that TLR8 activation in human macrophages

Analysis and quantification of vitamin D metabolites in serum by ultra-performance liquid chromatography coupled to tandem mass spectrometry and high-resolution mass spectrometry--a method comparison and validation.

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Rapid communications in mass spectrometry : RCM, 27(1), 200-206 (2012-12-15)

The aim of the work was to develop and validate a method for the quantification of vitamin D metabolites in serum using ultra-high-pressure liquid chromatography coupled to mass spectrometry (LC/MS), and to validate a high-resolution mass spectrometry (LC/HRMS) approach against

Vitamin D and cardiovascular disease: an appraisal of the evidence.

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Clinical chemistry, 60(4), 600-609 (2013-11-07)

Supplementation with vitamin D has received attention as a potential cardioprotective strategy. Biologically plausible mechanisms have been proposed to link vitamin D to coronary heart disease (CHD) prevention, and observational studies suggest an inverse association between serum 25-hydroxyvitamin D (25OHD)

Dietary vitamin D₂--a potentially underestimated contributor to vitamin D nutritional status of adults?

Kevin D Cashman et al.

The British journal of nutrition, 112(2), 193-202 (2014-05-02)

It has been suggested that vitamin D₂ is not very prevalent in the human food chain. However, data from a number of recent intervention studies suggest that the majority of subjects had measurable serum 25-hydroxyvitamin D₂ (25(OH)D₂) concentrations. Serum 25(OH)D₂

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條款

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我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

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重要文件

25-羟基维生素D2

≥95.0% (HPLC)

About This Item

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屬性

生物源

品質等級

化驗

形狀

顏色

mp

儲存溫度

SMILES 字串

InChI

InChI 密鑰

相關類別

描述

生化／生理作用

包裝

相關產品

相關產品

42579

安全資訊

象形圖

訊號詞

危險聲明

防範說明

危險分類

儲存類別代碼

水污染物質分類（WGK）

閃點（°F）

閃點（°C）

個人防護裝備

文件

分析證明 (COA)

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25-羟基维生素D₂