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Key Documents

Q0132

奎宁 硫酸酯

meets USP testing specifications, monograph mol wt. 782.94 ((C20H24N2O2)2 . H2SO4 . 2H2O)

同義詞:

奎宁 半硫酸盐 一水合物

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About This Item

經驗公式(希爾表示法):
C20H24N2O2 · 0.5H2O4S · H2O
CAS號碼:
分子量::
391.47
Beilstein:
6113937
MDL號碼:
分類程式碼代碼:
12352210
PubChem物質ID:
NACRES:
NA.21

agency

USP/NF
meets USP testing specifications

分子量

monograph mol wt. 782.94

mp

~225 °C (dec.) (lit.)

抗生素活性譜

parasites

作用方式

enzyme | inhibits

SMILES 字串

O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5

InChI

1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1

InChI 密鑰

ZHNFLHYOFXQIOW-LPYZJUEESA-N

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應用

Use to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites, the toxicity of heme (FP)-complexes and to inhibit mitochondrial ATP-regulated potassium channel.

生化/生理作用

钾通道阻滞剂。抗疟疾、抗胆碱能、抗高血压和降血糖剂;最初从南美树木的金鸡纳科中分离出来的生物碱。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

Lot/Batch Number

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J P Mooney et al.
Mucosal immunology, 7(6), 1302-1311 (2014-03-29)
Coinfection can markedly alter the response to a pathogen, thereby changing its clinical presentation. For example, non-typhoidal Salmonella (NTS) serotypes are associated with gastroenteritis in immunocompetent individuals. In contrast, individuals with severe pediatric malaria can develop bacteremic infections with NTS
Eva Woltmann et al.
Analytical and bioanalytical chemistry, 406(25), 6347-6362 (2014-08-12)
High production output of solid pharmaceutical formulations requires fast methods to ensure their quality. Likewise, fast analytical procedures are required in forensic sciences, for example at customs, to substantiate an initial suspicion. We here present the design and the optimization
Jie Ma et al.
Talanta, 143, 205-211 (2015-06-17)
Hollow cross-linked fluorescent carbon nitride nanoparticles (CNNPs) were fabricated via a facile one-pot solvothermal process. The obtained CNNPs were characterized by multiple analytical techniques including transmission electron microscopy (TEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), solid-state nuclear magnetic resonance
Miaomiao Zhang et al.
International journal of nanomedicine, 10, 6943-6953 (2015-11-27)
X-ray computed tomography (CT) is the most commonly used imaging technique for noninvasive diagnosis of disease. In order to improve tissue specificity and prevent adverse effects, we report the design and synthesis of iodine-doped carbon dots (I-doped CDs) as efficient

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