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D9900

Supelco

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1.0 mg/mL in methanol, analytical standard, for drug analysis

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About This Item

經驗公式(希爾表示法):
C16H13ClN2O
CAS號碼:
分子量::
284.74
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard, for drug analysis

品質等級

drug control

Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

濃度

1.0 mg/mL in methanol

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)

形式

single component solution

儲存溫度

2-8°C

SMILES 字串

CN1C(=O)CN=C(c2ccccc2)c3cc(Cl)ccc13

InChI

1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3

InChI 密鑰

AAOVKJBEBIDNHE-UHFFFAOYSA-N

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應用

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訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes,Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

51.8 °F - closed cup

閃點(°C)

11 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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Barbara Taferner et al.
Journal of medicinal chemistry, 54(15), 5349-5361 (2011-06-28)
A series of 31 analogues of the neolignan honokiol (a major constituent of Magnolia officinalis) was synthesized, and their effects on GABA(A) receptors expressed in Xenopus oocytes were investigated. Honokiol enhanced chloride currents (I(GABA)) through GABA(A) receptors of seven different
Shoukou Lee et al.
Bioorganic & medicinal chemistry, 16(21), 9519-9523 (2008-10-03)
The pyrimido[1,2-a][1,4]benzodiazepines (1a-c) and the 8-membered analogues (diazocines 2a and 2b) were separated into their atropisomers with HPLC on a chiral column. High stereochemical stability was observed in the atropisomer of the 8-membered derivatives (2a and 2b), and the 1,4-benzodiazepine
Erik Lager et al.
Journal of medicinal chemistry, 49(8), 2526-2533 (2006-04-14)
The 3-ethoxycarbonyl-4-quinolone compound 1 has previously been identified via a database search as an interesting lead compound for ligand binding at the benzodiazepine site of GABA(A) receptors (Kahnberg et al. J. Mol. Graphics Modelling 2004, 23, 253-261). Pharmacophore-guided optimization of
The translocator protein (18 kDa): central nervous system disease and drug design.
Alana M Scarf et al.
Journal of medicinal chemistry, 52(3), 581-592 (2009-01-13)
Jean-Baptiste Faure et al.
Epilepsia, 55(5), 644-653 (2014-03-14)
Temporal lobe epilepsy is a relatively frequent, invalidating, and often refractory neurologic disorder. It is associated with cognitive impairments that affect memory and executive functions. In the rat lithium-pilocarpine temporal lobe epilepsy model, memory impairment and anxiety disorder are classically

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