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RPTMAG-86K

Millipore

MILLIPLEX® 大鼠垂体磁珠面板-内分泌多重检测

The analytes available for this multiplex kit are: ACTH, BDNF, FSH, GH, LH, Prolactin, TSH.

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質等級

物種活性

rat

製造商/商標名

Milliplex®

assay range

accuracy: 75%
(GH)

accuracy: 88%
(ACTH)

accuracy: 89%
(LH)

accuracy: 90%
(TSH)

sensitivity: 0.38 pg/mL
(BDNF)

sensitivity: 0.87 pg/mL
(TSH)

sensitivity: 1.95 pg/mL
(ACTH)

sensitivity: 3.28 pg/mL
(LH)

sensitivity: 4.64 pg/mL
(Prolactin)

sensitivity: 6.50 pg/mL
(GH)

sensitivity: 7.62 pg/mL
(FSH)

standard curve range: 16-50,000 pg/mL
(GH, Prolactin)

standard curve range: 3.2-10,000 pg/mL
(ACTH, BDNF, LH, TSH)

standard curve range: 32-100,000 pg/mL
(FSH)

inter-assay cv: <20%
intra-assay cv: <10%

技術

multiplexing: suitable

檢測方法

fluorometric (Luminex xMAP)

運輸包裝

wet ice

一般說明

由于它控制许多其他内分泌腺,因此被称为主腺,垂体分泌许多关键激素,这些激素在代谢、生长和繁殖的调节中起重要作用。垂体激素负责刺激肾上腺(ACTH),甲状腺(TSH),卵巢和睾丸(FSH,LH)和母乳产生(催乳素),以及血压和肾脏排泄的水量。通过与垂体的联系,下丘脑通过检测激素水平来调节内分泌功能。脑源性神经营养因子(BDNF)是神经营养因子NGF家族的成员,是特定神经元亚群分化和存活所必需的。

MILLIPLEX® 大鼠垂体面板是一种7重试剂盒,用于同时定量大鼠血清或血浆样本、大鼠组织提取物或细胞/组织培养上清液样本中的以下任何或所有分析物:生长激素(GH)、促甲状腺激素(TSH)、促肾上腺皮质激素(ACTH)、促黄体生成激素(LH)、催乳素、促卵泡激素(FSH)和脑源性神经营养因子(BDNF)。该试剂盒采用96孔板,包含冻干标准混合物、两个内部检测质控品,最多可测量38份样本,一式两份。

Luminex® xMAP®平台使用磁珠免疫分析格式,以实现理想的速度和灵敏度,同时定量多种分析物,从而显著提高生产力,同时节省有价值的样品量。

面板类型:内分泌

應用

  • 分析物:促肾上腺皮质激素(ACTH)、脑源性神经营养因子(BDNF)、促卵泡激素(FSH)、生长激素(GH)、促黄体激素(LH)、催乳素、促甲状腺激素(TSH)
  • 推荐样品类型:大鼠血清、血浆、细胞/组织培养物上清液或裂解物
  • 推荐样品稀释度:每孔25 μL 1:3稀释的血清或血浆;细胞/组织培养样品可能需要在适当的对照培养基中稀释。
  • 分析运行时间:在2-8℃下过夜(16-18小时)
  • 研究类别:内分泌
  • 研究子类别:代谢

特點和優勢

通过在此面板中选择可用的分析物来设计多重试剂盒。

法律資訊

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

象形圖

Skull and crossbonesEnvironment

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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存取文件庫

Ivraym B Barsoum et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(7), 2657-2666 (2013-04-10)
Testes contain two distinct Leydig cell populations during development: fetal and adult Leydig cells (FLCs and ALCs, respectively). ALCs are not derived from FLCs, and it is unknown whether these two populations share common progenitors. We discovered that hedgehog (Hh)
Global but not gonadotrope-specific disruption of Bmal1 abolishes the luteinizing hormone surge without affecting ovulation.
Chu, A; Zhu, L; Blum, ID; Mai, O; Leliavski, A; Fahrenkrug, J; Oster, H; Boehm, U; Storch, KF
Endocrinology null
Vivi F H Jensen et al.
Scientific reports, 10(1), 5609-5609 (2020-03-30)
Maternal hypoglycaemia throughout gestation until gestation day (GD)20 delays foetal growth and skeletal development. While partially prevented by return to normoglycaemia after completed organogenesis (GD17), underlying mechanisms are not fully understood. Here, we investigated the pathogenesis of these changes and
Renee N Sadowski et al.
Neurotoxicology and teratology, 42, 17-24 (2014-01-21)
Previous work has shown that exposure to bisphenol A (BPA) can affect anxiety behavior. However, no studies have examined whether administration of this endocrine disruptor during the perinatal period has the potential to induce alterations in cognitive behavior in both
Vanessa D Sherk et al.
Medicine and science in sports and exercise, 51(12), 2465-2473 (2019-07-06)
The purpose of this study was to determine whether obesity and/or exercise training alters weight regain and musculoskeletal health after ovariectomy (OVX). Female rats were fed high-fat diet (HFD) to reveal obesity-prone (OP) and obesity-resistant (OR) phenotypes. The OP and

相關內容

Multiplex immunoassays, such as MILLIPLEX® multiplex metabolic assays, are critical in metabolic syndrome research because they provide a full picture of the different conditions related to it, like diabetes and obesity, as well as save time and sample volume.

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