528822

PARP Inhibitor XII

The PARP Inhibitor XII, also referenced under CAS 489457-67-2, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.

• 同義詞: PARP Inhibitor XII, 3-(4-Chlorophenyl)quinoxaline-5-carboxamide
• 經驗公式（希爾表示法）: C₁₅H₁₀ClN₃O
• CAS號碼: 489457-67-2
• 分子量：: 283.71
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: light brown
• 溶解度: DMSO: 10 mg/mL
• 運輸包裝: ambient
• 儲存溫度: 2-8°C

描述

一般說明

A potent quinoxaline-based PARP inhibitor with a ~5-fold selectivity towards PARP-2 over PARP-1 (IC₅₀ = 7 and 33 nM, respectively). Reported to be brain-permeant and exhibit good pharmacokinetics.

包裝

Packaged under inert gas

警告

Toxicity: Irritant (B)

其他說明

Ishida, J., et al. 2006. Bioorg. Med. Chem.14, 1378.
Iwashita, A., et al. 2005. FEBS Lett.579, 1389.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable