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Merck

5.00112

SAFC

Cocarboxylase chloride

thiamine diphosphoric acid ester chloride EMPROVE® API

製藥生產

同義詞:

Cocarboxylase chloride, Thiaminium diphosphoric acid ester chloride, Thiaminium pyrophosphate chloride, Thiaminium pyrophosphoric acid ester chloride, TPP

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About This Item

CAS號碼:
分子量::
460.77
MDL號碼:
分類程式碼代碼:
12352107
酶委員會索引編號:
205-836-1

品質等級

產品線

EMPROVE® API

形狀

solid

pH值

1.0-1.4 (20 °C, 100 g/L in H2O)

mp

240-244 °C (decomposition)

溶解度

220 g/L

體積密度

500 kg/m3

應用

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation

儲存溫度

2-25°C

SMILES 字串

[P](=O)([O-])(O[P](=O)(O)O)OCCc1[s]c[n+](c1C)Cc2c(nc(nc2)C)N.Cl

InChI

1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H

InChI 密鑰

YXVCLPJQTZXJLH-UHFFFAOYSA-N

一般說明

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Cocarboxylase chloride Emprove® API is a source for Vitamin B1 for use in clinical nutrition, vitamin supplements and infusion for Vitamin B1 deficiency. Cocarboxylase Chloride (thiamine diphosphoric acid ester chloride) Emprove® API is manufactured according to ICH Q7 guidelines. An ASMF is available.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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