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Merck

5.00111

SAFC

Cocarboxylase tetrahydrate

(thiamine pyrophosphate tetrahydrate), EMPROVE® API

製藥生產

同義詞:

Cocarboxylase tetrahydrate

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About This Item

經驗公式(希爾表示法):
C12H18N4O7P2S · 4H2O
CAS號碼:
分子量::
496.37
MDL號碼:
分類程式碼代碼:
12352107
酶委員會索引編號:
205-230-7

品質等級

產品線

EMPROVE® API

形狀

solid

pH值

2.4-3.2 (20 °C, 100 g/L in H2O)

溶解度

55 g/L

體積密度

450 kg/m3

應用

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation

儲存溫度

2-25°C

SMILES 字串

[P](=O)([O-])(O[P](=O)([O-])O)OCCc1[s]c[n+](c1C)Cc2c(nc(nc2)C)N.O.O.O.O.[H+]

InChI

1S/C12H18N4O7P2S.4H2O/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;;;;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);4*1H2

InChI 密鑰

KLOLNRGPRQYTIW-UHFFFAOYSA-N

一般說明

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Cocarboxylase tetrahydrate Emprove® API is a source for Vitamin B1 for use in clinical nutrition, vitamin supplements and infusion for Vitamin B1 deficiency. Cocarboxylase Tetrahydrate (thiamine diphosphoric acid ester tetrahydrate) Emprove® API is manufactured according to ICH Q7 guidelines. An ASMF is available.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

The substance 5.00111 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Ferenc Tóth et al.
Bone, 132, 115214-115214 (2019-12-31)
Bone morphogenetic protein 2 (BMP-2) is a member of the transforming growth factor-β superfamily, it is known to be a factor involved in skeletal development and capable of inducing in vitro osteogenic differentiation of mesenchymal stem cells (MSCs). Dental pulp

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

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