5.00111

Cocarboxylase tetrahydrate

(thiamine pyrophosphate tetrahydrate), EMPROVE^® API

• 同義詞: Cocarboxylase tetrahydrate
• 經驗公式（希爾表示法）: C₁₂H₁₈N₄O₇P₂S · 4H₂O
• CAS號碼: 68684-55-9
• 分子量：: 496.37
• MDL號碼: MFCD00150680
• 分類程式碼代碼: 12352107
• 酶委員會索引編號: 205-230-7

屬性

• 品質等級: 600
• 產品線: EMPROVE^® API
• 形狀: solid
• pH值: 2.4-3.2 (20 °C, 100 g/L in H₂O)
• 溶解度: 55 g/L
• 體積密度: 450 kg/m³
• 應用: liquid formulation; pharmaceutical; semi-solid formulation; solid formulation
• 儲存溫度: 2-25°C
• SMILES 字串: [P](=O)([O-])(O[P](=O)([O-])O)OCCc1[s]c[n+](c1C)Cc2c(nc(nc2)C)N.O.O.O.O.[H+]
• InChI: 1S/C12H18N4O7P2S.4H2O/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;;;;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);4*1H2
• InChI 密鑰: KLOLNRGPRQYTIW-UHFFFAOYSA-N

描述

一般說明

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Cocarboxylase tetrahydrate Emprove^® API is a source for Vitamin B1 for use in clinical nutrition, vitamin supplements and infusion for Vitamin B1 deficiency. Cocarboxylase Tetrahydrate (thiamine diphosphoric acid ester tetrahydrate) Emprove^® API is manufactured according to ICH Q7 guidelines. An ASMF is available.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

The substance 5.00111 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable