推薦產品
生物源
mouse
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
5A6, monoclonal
形狀
liquid
不包含
preservative
物種活性
rabbit, mouse, human
製造商/商標名
Calbiochem®
儲存條件
OK to freeze
avoid repeated freeze/thaw cycles
同型
IgG2
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... LRP1(4035)
一般說明
纯化的小鼠单克隆抗体。在非还原条件下可识别~85 kDa LRP轻链蛋白。
识别 〜85 kDa LRP 蛋白。
该抗LRP轻链小鼠mAb(5A6)经验证可用于冰冻切片、免疫印迹和石蜡切片,以检测LRP轻链。
免疫原
人
纯化人胎盘LRP
應用
冷冻切片(1-5 g/mLµ)
免疫印迹(1-5 µg/mL)
石蜡切片(1-5 µg/mL,请参阅应用参考文献)
免疫印迹(1-5 µg/mL)
石蜡切片(1-5 µg/mL,请参阅应用参考文献)
包裝
请参考小瓶标签的批号特定浓度。
警告
毒性:标准处理(A)
外觀
在100 mM NaCl,50 mM磷酸钠,1 mM EDTA,pH值6.6中。
重構
初次融化后,等分并冷冻(-20°C)。
其他說明
Mikhailenko, I., et al. 2001.J. Biol. Chem.276, 39484.
Rebeck, W.G., et al. 2001.Mol.Brain Res.87, 238.
Coukos, G., et al. 1994.Am. J. Pathol.144, 383.
Daugherty, A., and Rateri, D.L.1994.Arterioscler Thromb.14, 2017.
Strickland, D.K., et al. 1990.J. Biol. Chem.265, 17401.
Rebeck, W.G., et al. 2001.Mol.Brain Res.87, 238.
Coukos, G., et al. 1994.Am. J. Pathol.144, 383.
Daugherty, A., and Rateri, D.L.1994.Arterioscler Thromb.14, 2017.
Strickland, D.K., et al. 1990.J. Biol. Chem.265, 17401.
合适的工作稀释度由与测定条件相关的变量决定。
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Journal of molecular neuroscience : MN, 49(2), 277-288 (2012-09-05)
We previously reported that anti-amyloid-beta (Aβ) single-chain antibody (scFv59) brain delivery via recombinant adeno-associated virus (rAAV) was effective in reducing cerebral Aβ load in an Alzheimer's disease (AD) mouse model without inducing inflammation. Here, we investigated the prophylactic effects and
Journal of neuroimmunology, 319, 80-92 (2018-03-27)
We investigated the effects of granulocyte-macrophage colony stimulating factor (GM-CSF) on behavioral and pathological outcomes in Alzheimer's disease (AD) and non-transgenic mice. GM-CSF treatment in AD mice reduced brain amyloidosis, increased plasma Aβ, and rescued cognitive impairment with increased hippocampal
Alzheimer's & dementia : the journal of the Alzheimer's Association, 12(12), 1273-1287 (2016-06-22)
Memory loss and increased anxiety are clinical hallmarks of Alzheimer's disease (AD). Kallikrein-8 is a protease implicated in memory acquisition and anxiety, and its mRNA is known to be up-regulated in AD-affected human hippocampus. Therefore, an involvement of Kallikrein-8 in
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