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Merck
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重要文件

407256

Sigma-Aldrich

IGF-II, CF, Mouse, Recombinant

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About This Item

分類程式碼代碼:
12352202

化驗

≥97% (SDS-PAGE)

品質等級

形狀

solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze

雜質

<1.0 EU/μg protein Endotoxin

運輸包裝

ambient

儲存溫度

−20°C

一般說明

Recombinant, mouse insulin-like growth factor II (IGF-II) consisting of amino acids 25-91 and expressed in E. coli. Mouse IGF-II is synthesized as a 180 amino acid preproprecursor. Mature IGF-II is 91% and 97% amino acid identical to human and rat IGF-II, respectively.

生化/生理作用

ED₅₀ = 2-10 ng/ml as measured in a serum-free cell proliferation assay using MCF-7 human breast adenocarcinoma cells.

警告

Toxicity: Standard Handling (A)

外觀

Lyophilized from 0.2 µm sterile-filtered Acetonitrile, TFA.

重構

Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Reconstitute to 100 µg/ml in sterile PBS.

其他說明

Ostrovsky, O., et al. 2009. Mol. Biol. Cell20, 1855.
Chao, W. & P. A. DAmore, 2008. Cytokine Growth Factor Rev.19, 111.
Belfiore, A., 2007. Curr. Pharm. Des.13, 671.
Cornish, J., et al. 2007. Am. J. Physiol. Endocrinol. Metab.292,E117.
Merrick, D., et al. 2007. BMC Dev. Biol.7, 65.
Pavelic, J., et al. 2007. Indian J. Med. Res.125, 511.
VarelaNieto, I., et al. 2007. Curr. Pharm. Des.13,687.
Denley, A. et al. 2005. Cytokine Growth Factor Re,v.16, 421.
LeRoith, D. & C.T. Roberts Jr., 2003. Cancer Lett.195,127.
Buchanan, C.M., et al. 2001. Biochem. J.360, 431.
Werner, H. & D. LeRoith, 2000. Cell. Mol. Life Sci.57, 932.
Goya, L., et al. 1999. J. Biol. Chem.274 24633.
Daughaday, W.H., et al. 1993. Proc. Natl. Acad. Sci. USA90, 5823.
Holthuizen, P.E., et al. 1993. Regul. Pept.48, 77.
McCarthy, T.L., et al. 1992. Endocrinology130, 1303.
Zindy, F., et al. 1992. J. Hepatol.14, 30.
Rotwein, P. & L.J. Hall, 1990. DNA Cell Biol.10,725.
Rotwein, P., et al. 1988. Proc. Natl. Acad. Sci. USA85, 265.
Stempien, M.M., et al. 1986. DNA5, 357.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

4.1B - Flammable solid hazardous materials

水污染物質分類(WGK)

WGK 2


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