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Key Documents

14-377-M

Sigma-Aldrich

MKK4/SKK1 Protein, active, 10 µg

Active, N-terminal GST tagged, murine MKK4 residues 34-end, for use in Kinase Assays.

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物源

mouse

品質等級

100
300

分子量

Mw 67.7 kDa

製造商/商標名

Upstate®

技術

activity assay: suitable (kinase)

NCBI登錄號

UniProt登錄號

基因資訊

mouse ... MAP2K4(26398)

一般說明

N-terminal GST tagged, murine MKK4 residues 34-end
Product Source: expressed in E. coli

生化/生理作用

Protein Target: MKK4
Target Sub-Family: STE

包裝

Also available in 250 µg size --call for pricing and availability and reference catalog number 14-377M when ordering the 250 µg size.

品質

routinely evaluated by phosphorylation of ATF2 substrate

外觀

Purified using glutathione agarose. Activated by incubation with MEKK and then re-purified using Ni2+/NTA agarose

儲存和穩定性

6 months at -70C

其他說明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Y Fleming et al.
The Biochemical journal, 352 Pt 1, 145-154 (2000-11-04)
Stress-activated protein kinase 1 (SAPK1), also called c-Jun N-terminal kinase (JNK), becomes activated in vivo in response to pro-inflammatory cytokines or cellular stresses. Its full activation requires the phosphorylation of a threonine and a tyrosine residue in a Thr-Pro-Tyr motif

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