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Merck
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重要文件

07-692

Sigma-Aldrich

抗-Sar1抗体

Upstate®, from rabbit

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
無性繁殖:
polyclonal
application:
WB
物種活性:
monkey, mouse, rat, human
技術:
western blot: suitable
citations:
7

生物源

rabbit

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

monkey, mouse, rat, human

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ROR1(4919)

特異性

Sar1

免疫原

KLH缀合的合成肽,对应于人Sar1(a和b亚型)的氨基酸46-62(CKDDRLGQHVPTLHPTSE),其N端添加有半胱氨酸以进行缀合

應用

抗Sar1抗体经过验证可用在WB中检测Sar1。
研究子类别
G-蛋白

激酶 & 磷酸酶
研究类别
信号传导

品質

已通过免疫印迹法对3T3/A31细胞的RIPA裂解液进行了常规评估

標靶描述

Mr 21kDa

外觀

形式:纯化
蛋白A纯化

儲存和穩定性

自运送之日起在-20°C下稳定保存2年

分析報告

对照
阳性抗原对照:货号12-305,3T3/A31裂解液。添加2.5 μL 2-巯基乙醇/100 μL裂解液,煮沸5分钟以还原 制剂。在微凝胶每个泳道上样20 μg经还原的裂解液。

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Bethan Jones et al.
Nature genetics, 34(1), 29-31 (2003-04-15)
Dietary fat is an important source of nutrition. Here we identify eight mutations in SARA2 that are associated with three severe disorders of fat malabsorption. The Sar1 family of proteins initiates the intracellular transport of proteins in COPII (coat protein)-coated
A structural view of the COPII vesicle coat.
Bickford, Lincoln C, et al.
Current Opinion in Structural Biology, 14, 147-153 (2004)
Xue-Hai Liang et al.
Nucleic acids research, 46(19), 10225-10245 (2018-09-22)
RNase H1-dependent, phosphorothioate-modified antisense oligonucleotides (PS-ASOs) can enter cells through endocytic pathways and need to be released from the membrane-enclosed organelles, a limiting step for antisense activity. Accumulating evidence has suggested that productive PS-ASO release mainly occurs from late endosomes
The intracellular transport of chylomicrons requires the small GTPase, Sar1b.
Shoulders, Carol C, et al.
Current Opinion in Lipidology, 15, 191-197 (2004)
François-Xavier Campbell-Valois et al.
Molecular & cellular proteomics : MCP, 11(7), M111-M111 (2012-03-20)
Phagosomes, by killing and degrading pathogens for antigen presentation, are organelles implicated in key aspects of innate and adaptive immunity. Although it has been well established that phagosomes consist of membranes from the plasma membrane, endosomes, and lysosomes, the notion

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