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Merck
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重要文件

07-531

Sigma-Aldrich

Anti-PIR121-1/Sra-1 Antibody

Upstate®, from rabbit

同義詞:

Cytoplasmic FMR1-interacting protein 1, Specifically Rac1-associated protein 1, Sra-1, p140sra-1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

human, mouse

製造商/商標名

Upstate®

技術

immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... CYFIP1(23191)
mouse ... Cyfip1(20430)

特異性

PIR121-1/Sra-1 (aka CYFIP1)

免疫原

KLH-conjugated, synthetic peptide corresponding to amino acids 872-886 (SQEFQRDKQPNAQPQ-C) of human PIR121-1/Sra-1, with a C-terminal cysteine added for conjugation purposes.

應用

Anti-PIR121-1/Sra-1 Antibody is an antibody against PIR121-1/Sra-1 for use in IP & WB.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

品質

routinely evaluated by immunoblot on RIPA homogenates from rat brain

標靶描述

Mr~130kDa

外觀

Protein A purified
Format: Purified

儲存和穩定性

stable 2 years at -20°C from date of shipment

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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Anika Steffen et al.
The EMBO journal, 23(4), 749-759 (2004-02-07)
The Rho-GTPase Rac1 stimulates actin remodelling at the cell periphery by relaying signals to Scar/WAVE proteins leading to activation of Arp2/3-mediated actin polymerization. Scar/WAVE proteins do not interact with Rac1 directly, but instead assemble into multiprotein complexes, which was shown
Local F-actin network links synapse formation and axon branching.
Chia, PH; Chen, B; Li, P; Rosen, MK; Shen, K
Cell null
Patricia Kunda et al.
Current biology : CB, 13(21), 1867-1875 (2003-11-01)
In animal cells, GTPase signaling pathways are thought to generate cellular protrusions by modulating the activity of downstream actin-regulatory proteins. Although the molecular events linking activation of a GTPase to the formation of an actin-based process with a characteristic morphology
Marco A Salazar et al.
The Journal of biological chemistry, 278(49), 49031-49043 (2003-09-25)
Tuba is a novel scaffold protein that functions to bring together dynamin with actin regulatory proteins. It is concentrated at synapses in brain and binds dynamin selectively through four N-terminal Src homology-3 (SH3) domains. Tuba binds a variety of actin
Reply to "Reduced CYFIP2 Stability by Arg87 Variants Causing Human Neurological Disorders".
Mitsuko Nakashima et al.
Annals of neurology, 86(5), 805-806 (2019-09-12)

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