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Merck
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重要文件

GW21143

Sigma-Aldrich

Anti-AP-1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-Activator protein 1, Anti-Transcription factor AP-1

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

chicken

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

mouse, human, rat

製造商/商標名

Genway 15-288-21143

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... JUN(3725)

免疫原

Immunogen Sequence: GI # 4758616, sequence 1-240
Recombinant V-jun avian sarcoma virus 17 oncogene homolog

應用

Anti-AP-1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

c-Jun is a protein encoded by the JUN gene in humans. c-Jun in combination with c-Fos results in the formation of the AP-1 early response transcription factor. It is crucially involved in propagation of macrophage-driven inflammatory networks. AP1 may guide for the treatment decisions for endometriosis management and may provide a mechanistic endpoint for assessing efficacy of new agents aimed at curtailing inflammatory mechanisms that drive disease progression. It may possibly be utilized for the treatment of HPV-induced cervical cancers.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Science translational medicine, 6(222), 222ra16-222ra16 (2014-02-07)
Clinical management of endometriosis is limited by the complex relationship between symptom severity, heterogeneous surgical presentation, and variability in clinical outcomes. As a complement to visual classification schemes, molecular profiles of disease activity may improve risk stratification to better inform
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