05-1317

Anti-SUZ12 Antibody, clone 2AO9

clone 2AO9, from mouse

• 同義詞: ChET 9 protein, Chromatin precipitated E2F target 9 protein, Joined to JAZF1 protein, Suppressor of zeste 12 protein homolog, joined to JAZF1, suppressor of zeste 12 homolog (Drosophila)
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 2AO9, monoclonal
• 物種活性: human
• 物種活性（以同源性預測）: rabbit (based on 100% sequence homology)
• 技術: ChIP: suitable; immunocytochemistry: suitable; immunoprecipitation (IP): suitable
• 同型: IgG
• NCBI登錄號: NP_056170.2
• UniProt登錄號: Q15022
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SUZ12(23512)

描述

一般說明

SUZ12 is a polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. This protein is component of the PRC2 complex, which methylates ′Lys-9′ and ′Lys-27′ residues of histone H3.

特異性

This antibody recognizes SUZ12.

免疫原

Epitope: Unknown

Recombinant protein corresponding to human SUZ12.

應用

Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC. Pasini, D., et al. (2007). Molecular and Cellular Biology. 27(10):3769–3779.

Chromatin Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in ChiP. Pasini, D., et al. (2007). Molecular and Cellular Biology. 27(10):3769–3779.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Chromatin Biology

Use Anti-SUZ12 Antibody, clone 2AO9 (Mouse Monoclonal Antibody) validated in IP, ICC to detect SUZ12 also known as ChET 9 protein, Chromatin precipitated E2F target 9 protein, Joined to JAZF1 protein.

品質

Evaluated by Immunoprecipitation in HeLa cell lysate.

Immunoprecipitation Analysis: 10 µg/mL of this antibody immunoprecipitated SUZ12 in HeLa cells.

標靶描述

~ 95 kDa

外觀

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
HeLa cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable