901568

Bromo-PEG₃-acid

• 經驗公式（希爾表示法）: C₉H₁₇BrO₅
• CAS號碼: 782475-35-8
• 分子量：: 285.13
• MDL號碼: MFCD22574820
• 分類程式碼代碼: 12352101
• NACRES: NA.22

屬性

• 形狀: liquid
• 反應適用性: reagent type: linker
• 官能基: bromo; carboxylic acid
• 儲存溫度: −20°C
• SMILES 字串: BrCCOCCOCCOCCC(O)=O
• InChI 密鑰: OKWHCSUISPMYIJ-UHFFFAOYSA-N

描述

應用

Bromo-PEG₃-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG₃-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility.

法律資訊

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3