790451

TCO-amine HCl salt

• 同義詞: trans-Cyclooctene-amine hydrochloride salt, TCO-NH2, HCl salt
• 經驗公式（希爾表示法）: C₁₂H₂₂N₂O₂ · HCl
• 分子量：: 262.78
• 分類程式碼代碼: 12352116
• PubChem物質ID: 329768216
• NACRES: NA.22

屬性

• 形狀: solid
• 反應適用性: reaction type: click chemistry; reagent type: linker
• 官能基: amine
• 儲存溫度: −20°C
• SMILES 字串: O=C(NCCCN)OC1CCC/C=C/CC1.[H]Cl
• InChI: 1S/C12H22N2O2.ClH/c13-9-6-10-14-12(15)16-11-7-4-2-1-3-5-8-11;/h1-2,11H,3-10,13H2,(H,14,15);1H/b2-1+;
• InChI 密鑰: GIYQQURLGCGUKK-TYYBGVCCSA-N

描述

應用

Amine functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into carboxyl containing compounds or biomolecules via standard coupling techniques (DCC; EDC etc...). Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable