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生物源
human
重組細胞
expressed in E. coli
化驗
≥90% (SDS-PAGE)
形狀
liquid
分子量
40.4 kDa (377 aa, 1-357 aa + NT His Tag)
包裝
pkg of 100 μg
儲存條件
avoid repeated freeze/thaw cycles
NCBI登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... SORD(6652)
一般說明
SORD, also known as L-iditol 2-dehydrogenase or SORD1, is a 357 amino acid member of the zinc containing alcohol dehydrogenase family. It is widely expressed with highest expression in kidney and in the lens of the eye. SORD enzymatically catalyzes the zinc-dependent interconversion of polyols, such as sorbitol and xylitol, to their respective ketoses.
外觀
0.5 mg/mL solution in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 5 mM DTT and 20% glycerol.
準備報告
Centrifuge the vial prior to opening.
其他說明
MGSSHHHHHH SSGLVPRGSH MAAAAKPNNL SLVVHGPGDL RLENYPIPEP GPNEVLLRMH SVGICGSDVH YWEYGRIGNF IVKKPMVLGH EASGTVEKVG SSVKHLKPGD RVAIEPGAPR ENDEFCKMGR YNLSPSIFFC ATPPDDGNLC RFYKHNAAFC YKLPDNVTFE EGALIEPLSV GIHACRRGGV TLGHKVLVCG AGPIGMVTLL VAKAMGAAQV VVTDLSATRL SKAKEIGADL VLQISKESPQ EIARKVEGQL GCKPEVTIEC TGAEASIQAG IYATRSGGTL VLVGLGSEMT TVPLLHAAIR EVDIKGVFRY CNTWPVAISM LASKSVNVKP LVTHRFPLEK ALEAFETFKK GLGLKIMLKC DPSDQNP
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Nature communications, 4, 2434-2434 (2013-09-12)
Carbohydrates with high glycaemic index are proposed to promote the development of obesity, insulin resistance and fatty liver, but the mechanism by which this occurs remains unknown. High serum glucose concentrations are known to induce the polyol pathway and increase
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