SML3533
BAY-0361
≥95% (HPLC)
别名:
(S)-2-(3-Cyano-2-(2′-fluoro-3′-methylbiphenyl-4-yl)-1,7-naphthyridin-4-ylamino)butanoic acid, BAY 0361, BAY 091 inactive control, BAY 091 negative control, BAY-091 inactive control, BAY-091 negative control, BAY0361, BAY091 inactive control, BAY091 negative control
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About This Item
经验公式（希尔记法）:
C26H21FN4O2
分子量:
440.47
分類程式碼代碼:
12352200
NACRES:
NA.77
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品質等級
化驗
≥95% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 2 mg/mL, clear
儲存溫度
2-8°C
SMILES 字串
N#CC1=C(N=C2C=NC=CC2=C1N[C@@H](CC)C(O)=O)C3=CC=C(C=C3)C4=C(C(C)=CC=C4)F
生化／生理作用
BAY-0361 is the inactive enantiomer of and negative control for the potent and highly selective PIP4K2A inhibitor BAY-091.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Lars Wortmann et al.
Journal of medicinal chemistry, 64(21), 15883-15911 (2021-10-27)
PIP4K2A is an insufficiently studied type II lipid kinase that catalyzes the conversion of phosphatidylinositol-5-phosphate (PI5P) into phosphatidylinositol 4,5-bisphosphate (PI4,5P2). The involvement of PIP4K2A/B in cancer has been suggested, particularly in the context of p53 mutant/null tumors. PIP4K2A/B depletion has
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